Extracellular purines, principally adenosine triphosphate and adenosine, are among the
oldest evolutionary and widespread chemical messengers. The integrative view of …

Human mesenchymal stem cells (MSCs) are a rare population of non-hematopoietic stem
cells with multilineage potential, originally identified in the bone marrow. Due to the lack of a …

Extracellular ATP, related nucleotides and adenosine are among the earliest signaling
molecules, operating in virtually all tissues and cells. Through their specific receptors …

Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into bone forming
cells. Such ability is compromised in elderly individuals resulting in bone disorders such as …

The presented results show for the first time that the neurogenic transdifferentiation of hUC‐
MSCs considerably changes the elements of purinergic signaling profile. Although, it has …

Mesenchymal stem cells (MSCs) have shown a great potential for cell‐based therapy and
many different therapeutic purposes. Despite the recent advances in the knowledge of …

The role played by mesenchymal stem cells (MSCs) in contributing to adult tissue
homeostasis and damage repair thanks to their differentiation capabilities has raised a great …

Mesenchymal stem cells (MSCs) are population of adult stem cells and attractive candidates
for cartilage repair due to their chondrogenic potential. Purinergic compounds (purinergic …

Human mesenchymal or stromal cells (hMSCs) isolated from various adult tissues are
primary candidates in cell therapy and tissue regeneration. Despite promising results in …

Extracellular nucleotides are potent signaling molecules mediating cell-specific biological
functions, mostly within the processes of tissue damage and repair and flogosis. We …