Initiation and maintenance of labor in humans is associated with an increase in
prostaglandin synthesis by intrauterine tissues. The objective of the present study was to …

Increased prostaglandin (PG) synthesis by fetal membranes occurs at parturition. PGE2
synthesis from arachidonic acid involves multiple enzymes and two isoforms of the terminal …

We have evaluated the effect of chorioamnionitis on the protein expression of microsomal
and cytosolic prostaglandin E2 synthases (mPGES and cPGES) in preterm human …

Abstract Prostaglandin E2 (PGE2) is considered important for blastocyst spacing,
implantation, and decidualization in the rodent uterus. PGE synthase (PGES) catalyzes the …

First published August 15, 2001; 10.1152/ajprenal. 00116.2001.—PGE2 plays a critical role
in regulating renal function and facilitating reproduction. One of the rate-limiting biosynthetic …

Since the controversies regarding the use of non-steroidal anti-inflammatory drugs (NSAIDs)
and selective cyclo-oxygenase (COX)-2 antagonists for the treatment of preterm labour …

Prostaglandins are involved in the regulation of several reproductive processes such as
ovulation, luteolysis, and establishment of pregnancy. Prostaglandin E2 (PGE2) appears to …

Increased prostaglandin E2 (PGE2) synthesis involves multiple enzymes and two isoforms
of the terminal enzyme of this biosynthetic pathway, PGE synthase (PGES), were recently …

This study was designed to determine the regulatory effect of glucocorticoid and estradiol on
expression of ovine intrauterine membrane-associated prostaglandin E2 synthase 1 …

Prostaglandins (PGs) act as potent uterotonins at the time of labor. Prostaglandin E synthase
(PGES) is responsible for the formation of PGE2, a uterotonin. PGI2 is synthesized by the …