Identification of novel nutrient-sensitive gene regulatory networks in amniocytes from fetuses with spina bifida
M White, J Arif-Pardy, KL Connor - Reproductive Toxicology, 2023 - Elsevier
Neural tube defects (NTDs) remain among the most common congenital anomalies.
Contributing risk factors include genetics and nutrient deficiencies, however, a …
Contributing risk factors include genetics and nutrient deficiencies, however, a …
Identification of novel nutrient-sensitive gene regulatory networks in amniotic fluid from fetuses with spina bifida using miRNA and transcription factor network analysis
M White, J Arif-Pardy, KL Connor - medRxiv, 2022 - medrxiv.org
Abstract Background Neural tube defects (NTDs) remain among the most common
congenital anomalies. Contributing risk factors include genetics and nutrient deficiencies …
congenital anomalies. Contributing risk factors include genetics and nutrient deficiencies …
Micronutrient imbalance and common phenotypes in neural tube defects
AD Kakebeen, L Niswander - genesis, 2021 - Wiley Online Library
Neural tube defects (NTDs) are among the most common birth defects, with a prevalence of
close to 19 per 10,000 births worldwide. The etiology of NTDs is complex involving the …
close to 19 per 10,000 births worldwide. The etiology of NTDs is complex involving the …
Fetal spina bifida associates with dysregulation in nutrient‐sensitive placental gene networks: Findings from a matched case–control study
M White, J Arif‐Pardy, T Van Mieghem… - Clinical and …, 2024 - Wiley Online Library
To improve outcomes in fetuses with spina bifida (SB), better understanding is needed of the
molecular drivers of SB and its comorbidities. Pregnant people carrying a fetus with isolated …
molecular drivers of SB and its comorbidities. Pregnant people carrying a fetus with isolated …
Exploring epigenomic mechanisms of neural tube defects using multi‐omics methods and data
W Huang, Z Yuan, H Gu - Annals of the New York Academy of …, 2022 - Wiley Online Library
Neural tube defects (NTDs) are a heterogeneous set of malformations attributed to
disruption in normal neural tube closure during early embryogenesis. An in‐depth …
disruption in normal neural tube closure during early embryogenesis. An in‐depth …
[HTML][HTML] Intersection of complex genetic traits affecting maternal metabolism, fetal metabolism, and neural tube defect risk: looking for needles in multiple haystacks
MR Loeken - Molecular genetics and metabolism, 2014 - ncbi.nlm.nih.gov
Neural tube defects (NTDs) are among the most common birth defects (1 in 1000 live births);
while their etiology is still not well understood, current evidence indicates that both genetic …
while their etiology is still not well understood, current evidence indicates that both genetic …
Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects
Background Neural tube closure defects (NTDs) are among the most common congenital
malformation in human, typically presenting in liveborns as spina bifida. At least 240 gene …
malformation in human, typically presenting in liveborns as spina bifida. At least 240 gene …
Gene–environment interactions underlying the etiology of neural tube defects
CD Caiaffa, CSR Fonteles, L Yunping… - Current Topics in …, 2023 - Elsevier
Neural tube defects (NTDs) consist of severe structural malformations of the brain and spinal
cord and are the second most common structural birth defect in humans, accounting for …
cord and are the second most common structural birth defect in humans, accounting for …
Mouse as a model for multifactorial inheritance of neural tube defects
IE Zohn - Birth Defects Research Part C: Embryo Today …, 2012 - Wiley Online Library
Neural tube defects (NTDs) such as spina bifida and anencephaly are some of the most
common structural birth defects found in humans. These defects occur due to failures of …
common structural birth defects found in humans. These defects occur due to failures of …
Alteration of the microRNA expression profile and identification of miRNA/mRNA negative regulation pairs in neural tube defects
J Zhang, L Yang, J Yu, Q Yang, J Mu… - Acta Biochimica et …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small, noncoding transcripts, and∼ 22 nucleotides long, which
belong to a class of endogenous small regulatory RNA molecules that target mRNAs and …
belong to a class of endogenous small regulatory RNA molecules that target mRNAs and …