No genetic causal association between periodontitis and arthritis: A bidirectional two-sample mendelian randomization analysis

KJ Yin, JX Huang, P Wang, XK Yang, SS Tao… - Frontiers in …, 2022 - frontiersin.org
Objectives Periodontitis (PD) has been linked to arthritis in previous epidemiological
observational studies; however, the results are inconclusive. It remains unclear whether the …

Association between inflammatory bowel disease and periodontitis: a bidirectional two‐sample Mendelian randomization study

Z Wang, S Li, D Tan, W Abudourexiti… - Journal of Clinical …, 2023 - Wiley Online Library
Abstract Aim This Mendelian randomization (MR) study was performed to explore the
potential bidirectional causal association between inflammatory bowel disease (IBD) and …

Periodontal disease in individuals with a genetic risk of developing arthritis and early rheumatoid arthritis: a cross‐sectional study

JM Bello‐Gualtero, GI Lafaurie, LX Hoyos… - Journal of …, 2016 - Wiley Online Library
Background: Recent consensus emphasizes the importance of studying individuals at risk
for rheumatoid arthritis (pre‐RA) and those with early RA (eRA). Periodontal tissues have …

Rheumatoid arthritis risk associated with periodontitis exposure: a nationwide, population-based cohort study

YY Chou, KL Lai, DY Chen, CH Lin, HH Chen - PloS one, 2015 - journals.plos.org
Background The risk of periodontitis (PD) is increased in the patient group of rheumatoid
arthritis (RA). RA and PD also shared some pathological mechanism. The aim of this study is …

Bidirectional relationship between osteoarthritis and periodontitis: a population-based cohort study over a 15-year follow-up

KSK Ma, JN Lai, E Thota, HT Yip, NC Chin… - Frontiers in …, 2022 - frontiersin.org
Objective To identify the relationship between osteoarthritis and periodontitis. Methods
144,788 periodontitis patients and 144,788 propensity score-matched controls without …

Hand to mouth: a systematic review and meta-analysis of the association between rheumatoid arthritis and periodontitis

NR Fuggle, TO Smith, A Kaul, N Sofat - Frontiers in immunology, 2016 - frontiersin.org
Background Rheumatoid arthritis (RA) and periodontitis are both chronic inflammatory
diseases, which demonstrate similarities in terms of mechanism, histopathology, and …

Does periodontitis represent a risk factor for rheumatoid arthritis? A systematic review and meta-analysis

R de Oliveira Ferreira, R de Brito Silva… - Therapeutic …, 2019 - journals.sagepub.com
Periodontitis is an inflammatory disease of dental supporting tissues (gingiva, periodontal
ligament, and bone) and it has been suggested as a possible etiology for rheumatoid …

Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci

M Munz, GM Richter, BG Loos, S Jepsen… - European Journal of …, 2019 - nature.com
Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11%
worldwide for the severe forms and an estimated heritability of 50%. It is classified into the …

Testing the association between tobacco smoking, alcohol consumption, and risk of periodontitis: A Mendelian randomization study

SE Baumeister, D Freuer, M Nolde… - Journal of clinical …, 2021 - Wiley Online Library
Aim To investigate the associations of tobacco smoking and alcohol consumption with
periodontitis using Mendelian randomization (MR) analysis. Materials and methods We …

Is there a bidirectional association between rheumatoid arthritis and periodontitis? A systematic review and meta-analysis

SB Hussain, J Botelho, V Machado, SA Zehra… - Seminars in arthritis and …, 2020 - Elsevier
Background Several lines of evidence suggest a bi-directional association between
Rheumatoid Arthritis (RA) and Periodontitis (PD). Our aim was to systematically appraise the …