Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Tailoring inorganic nanoadjuvants towards next-generation vaccines

X Li, X Wang, A Ito - Chemical Society Reviews, 2018 - pubs.rsc.org
Vaccines, one of the most effective and powerful public health measures, have saved
countless lives over the past century and still have a tremendous global impact. As an …

Nanomaterial-based vaccine adjuvants

B Sun, T Xia - Journal of materials chemistry B, 2016 - pubs.rsc.org
Vaccination is a biological process that administers antigenic materials to stimulate an
individual's immune system to develop immunity to a specific pathogen. It is the most …

Nanoparticle formulated vaccines: opportunities and challenges

P Lung, J Yang, Q Li - Nanoscale, 2020 - pubs.rsc.org
Vaccines harness the inherent properties of the immune system to prevent diseases or treat
existing ones. Continuous efforts have been devoted to both gaining a mechanistic …

Understanding structure–function relationships of nanoadjuvants for enhanced cancer vaccine efficacy

J Tan, B Ding, B Teng, P Ma… - Advanced Functional …, 2022 - Wiley Online Library
Adjuvant, as an important part of vaccines, can observably enhance the magnitude, breadth
and durability of immune responses. Nanoadjuvants, as novel vaccine adjuvants, have …

Applications of nanomaterials as vaccine adjuvants

M Zhu, R Wang, G Nie - Human vaccines & immunotherapeutics, 2014 - Taylor & Francis
Vaccine adjuvants are applied to amplify the recipient's specific immune responses against
pathogen infection or malignancy. A new generation of adjuvants is being developed to …

Rational vaccinology: harnessing nanoscale chemical design for cancer immunotherapy

Z Huang, CE Callmann, S Wang, MK Vasher… - ACS Central …, 2022 - ACS Publications
Cancer immunotherapy is a powerful treatment strategy that mobilizes the immune system to
fight disease. Cancer vaccination is one form of cancer immunotherapy, where …

[HTML][HTML] Progress towards adjuvant development: focus on antiviral therapy

A Brai, F Poggialini, C Pasqualini, CI Trivisani… - International Journal of …, 2023 - mdpi.com
In recent decades, vaccines have been extraordinary resources to prevent pathogen
diffusion and cancer. Even if they can be formed by a single antigen, the addition of one or …

Advanced nanovaccines based on engineering nanomaterials for accurately enhanced cancer immunotherapy

D Wang, W Gu, W Chen, J Zhou, L Yu, BK Kim… - Coordination Chemistry …, 2022 - Elsevier
In recent years, nanovaccine based on nanomaterials emerging as an advanced
nanotechnology has drawn more attention for accurately enhancing anti-tumor …

[HTML][HTML] Methodical design of viral vaccines based on avant-Garde nanocarriers: A multi-domain narrative review

E Raoufi, B Bahramimeimandi, M Salehi-Shadkami… - Biomedicines, 2021 - mdpi.com
The current health crisis caused by coronavirus 2019 (COVID-19) and associated
pathogens emphasize the urgent need for vaccine systems that can generate protective and …