Biological and physiological role of reactive oxygen species–the good, the bad and the ugly

L Zuo, T Zhou, BK Pannell, AC Ziegler… - Acta …, 2015 - Wiley Online Library
Reactive oxygen species (ROS) are chemically reactive molecules that are naturally
produced within biological systems. Research has focused extensively on revealing the …

Modulation of reactive oxygen species in health and disease

S Habtemariam - Antioxidants, 2019 - mdpi.com
In diverse living organisms, signaling within the cell, chemical communication between cells
or simply the fate of cells to survive or die is largely dependent on the intricate balance of …

Reactive oxygen species in health and disease

AA Alfadda, RM Sallam - BioMed research international, 2012 - Wiley Online Library
During the past decades, it became obvious that reactive oxygen species (ROS) exert a
multitude of biological effects covering a wide spectrum that ranges from physiological …

New insight into the role of reactive oxygen species (ROS) in cellular signal-transduction processes

EG Russell, TG Cotter - International review of cell and molecular biology, 2015 - Elsevier
Reactive oxygen species (ROS) were once considered to be deleterious agents,
contributing to a vast range of pathologies. But, now their protective effects are being …

[HTML][HTML] Reactive oxygen species: The dual role in physiological and pathological conditions of the human body

SK Bardaweel, M Gul, M Alzweiri… - The Eurasian journal …, 2018 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) are well-known for playing a dual role as destructive and
constructive species. Indeed, ROS are engaged in many redox-governing activities of the …

Reactive oxygen species and oxidative stress

C Migdal, M Serres - Medecine Sciences: M/S, 2011 - europepmc.org
Oxidative stress is defined as an imbalance between the production of reactive oxygen
species (ROS) and the antioxidant capacity of the cell. For long, ROS have been considered …

ROS and diseases: Role in metabolism and energy supply

S Yang, G Lian - Molecular and cellular biochemistry, 2020 - Springer
Researches dedicated to reactive oxygen species (ROS) had been performed for decades,
yet the outcomes remain controversial. With the relentless effort of studies, researchers have …

Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications

AI Casas, VTV Dao, A Daiber, GJ Maghzal… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Enhanced levels of reactive oxygen species (ROS) have been associated with
different disease states. Most attempts to validate and exploit these associations by chronic …

[HTML][HTML] Cellular Red-Ox system in health and disease: The latest update

AB Jena, RR Samal, NK Bhol, AK Duttaroy - Biomedicine & …, 2023 - Elsevier
Cells are continually exposed to reactive oxygen species (ROS) generated during cellular
metabolism. Apoptosis, necrosis, and autophagy are biological processes involving a …

Short overview of ROS as cell function regulators and their implications in therapy concepts

L Milkovic, A Cipak Gasparovic, M Cindric, PA Mouthuy… - Cells, 2019 - mdpi.com
The importance of reactive oxygen species (ROS) has been gradually acknowledged over
the last four decades. Initially perceived as unwanted products of detrimental oxidative …