Tobacco smoke (TS) contains numerous cancer-causing agents, with polycyclic aromatic
hydrocarbons (PAHs) and nitrosamines being most frequently cited as the major TS human …

The allure of tobacco smoking is linked to the instant gratification provided by inhaled
nicotine. Unfortunately, tobacco curing and burning generates many mutagens including …

Second-hand smoke (SHS) is associated with 20–30% of cigarette-smoke related diseases,
including cancer. Majority of SHS (> 80%) originates from side-stream smoke (SSS) …

DNA adducts are believed to play a central role in the induction of cancer in cigarette
smokers and are proposed as being potential biomarkers of cancer risk. We have …

DNA adducts play a central role in chemical carcinogenesis. The analysis of formation and
repair of smoking‐related DNA adducts remains particularly challenging as both smokers …

Human lymphoid cells (Raji) were exposed to water-soluble compounds from cigarette
smoke (CS) generated in a smoking machine. DNA damage, as detected by alkaline single …

Cigarette smoking and the use of smokeless chewing tobacco have been closely tied to the
development of several human cancers, including lung, oral, esophageal, and bladder …

The complexity of tobacco smoke leads to some confusion about the mechanisms by which
it causes lung cancer. Among the multiple components of tobacco smoke, 20 carcinogens …

Tobacco use continues to be a major cause of cancer in the developed world, and despite
significant progress in this country in tobacco control, which is driving a decrease in cancer …

DNA adducts associated with tobacco smoking could provide a marker of biologically
effective dose of tobacco carcinogens and improve individual cancer risk prediction. A …