The tachykinins, exemplified by substance P, are one of the most intensively studied
neuropeptide families. They comprise a series of structurally related peptides that derive …

Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …

The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …

There is an expanding repertoire of mammalian tachykinins produced by a variety of
tachykinin genes, gene splicing events and peptide processing. Novel tachykinin-binding …

Tachykinins are widely distributed in the peripheral nervous system of the respiratory,
urinary and gastrointestinal tract, stored in enteric neurons and in peripheral nerve endings …

Tachykinins (TKs) constitute the largest vertebrate brain/gut peptide family. Since discovery
of Substance P as a structurally unidentified vasodilatory and contractile compound in 1931 …

The mammalian tachykinins (substance P, neurokinin A, and neurokinin B) are widely
distributed throughout the central and peripheral nervous systems, where they act as …

In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide
number of peptides with neurotransmitter activity have been identified in the past few years …

The tachykinin peptide family certainly represents one of the largest peptide families
described in the animal organism. So far, more than 40 tachykinins have been isolated from …

Throughout the past decade, major advances have been made in our understanding of the
biology of the mammalian tachykinin neuropeptides. It is now well established that …