During the last two decades, an increasing number of reports have pointed out that the
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …

Polyethylene glycol (PEG) is a common ingredient in nanomedicines and pharmaceuticals.
Recent studies show that approximately 20–70% of humans have anti-PEG antibodies that …

Since the early days marking the first use of nanomedicine in the early 80s, there has been a
meaningful change in the scientific field involving the Fabrication, characterization, and …

Despite the clinical introduction of an increasing number of polyethylene glycol (PEG)-
conjugated substances, PEG has been named as the cause of an unexpected immunogenic …

The modification of protein and nanoparticle therapeutics with polyethylene glycol (PEG), a
flexible, uncharged, and highly hydrophilic polymer, is a widely adopted approach to reduce …

PEGylation technique is currently considered the gold standard approach to provide a long
and safe circulation of drugs. Although this is the accepted dogma, various clinical reports …

Particles with a size range of 1–100 nm used in various fields of life sciences are called
nanoparticles (NPs). Currently, nanotechnology has a wide range of applications in …

Engineered nanoparticles (NPs) have broad applications in industry and nanomedicine.
When NPs enter the body, interactions with the immune system are unavoidable. The innate …

Nanoparticle interactions with various components of the immune system are determined by
their physicochemical properties such as size, charge, hydrophobicity and shape …

Nanoparticles (NPs) have promising applications in medicine. Immune system is an
important protective system to defend organisms from non‐self matters. NPs interact with the …