The sense of taste plays a critical role in the life and nutritional status of humans and other
organisms. Human taste perception may be categorized according to four well known and …

In the oral cavity, taste receptor cells dedicate to detecting chemical compounds in foodstuffs
and transmitting their signals to gustatory nerve fibers. Heretofore, five taste qualities (sweet …

Bitter taste in mammals is achieved by a family of approximately 30 bitter taste receptor
genes. The main function of bitter taste is to protect the organism against the ingestion of …

Taste receptor cells use a variety of mechanisms to transduce chemical information into
cellular signals. Seven-transmembrane-helix receptors initiate signaling cascades by …

The discovery of two families of mammalian taste receptors has provided important insights
into taste recognition and taste perception. Recent studies have examined the receptors and …

An ever increasing number of reports about taste receptors in non-gustatory tissues suggest
that these molecules must have additional functions apart from taste. Of the extraoral tissues …

The identification of two families of receptors, T1Rs and T2Rs, for sweet and bitter taste
stimuli has opened the door to understanding some of the basic mechanisms underlying …

Sweetness is the preferred taste of humans and many animals, likely because sugars are a
primary source of energy. In many mammals, sweet compounds are sensed in the tongue by …

The discovery of the T1R family of Class CG protein-coupled receptors in the peripheral
gustatory system a decade ago has been a tremendous advance for taste research, and its …

A vast number of structurally diverse bitter compounds need to be detected by a subfamily of
only~ 25 human bitter receptors. Failure in detecting them might be lethal, since some …