Emerging hallmarks of metabolic reprogramming in prostate cancer

F Lasorsa, NA di Meo, M Rutigliano, M Ferro… - International Journal of …, 2023 - mdpi.com
Prostate cancer (PCa) is the most common male malignancy and the fifth leading cause of
cancer death in men worldwide. Prostate cancer cells are characterized by a hybrid …

The metabolic landscape of prostate cancer

F Giunchi, M Fiorentino, M Loda - European urology oncology, 2019 - Elsevier
Context Neoplastic cells are characterized by metabolic alterations that sustain tumor
growth. Interventions aimed at modifying metabolic rewiring of cancer cells are currently …

Revisiting prostate cancer metabolism: From metabolites to disease and therapy

HJ Cardoso, TMA Carvalho… - Medicinal Research …, 2021 - Wiley Online Library
Prostate cancer (PCa), one of the most commonly diagnosed cancers worldwide, still
presents important unmet clinical needs concerning treatment. In the last years, the …

Glucose metabolism in the progression of prostate cancer

F Cutruzzola, G Giardina, M Marani, A Macone… - Frontiers in …, 2017 - frontiersin.org
Prostate cancer is one of the most common types of cancer in western country males but the
mechanisms involved in the transformation processes have not been clearly elucidated …

Metabolic regulation of prostate cancer heterogeneity and plasticity

C Peitzsch, I Gorodetska, D Klusa, Q Shi… - Seminars in cancer …, 2022 - Elsevier
Metabolic reprogramming is one of the main hallmarks of cancer cells. It refers to the
metabolic adaptations of tumor cells in response to nutrient deficiency, microenvironmental …

Metabolomic profiling for the identification of novel diagnostic markers and therapeutic targets in prostate cancer: An update

G Lucarelli, D Loizzo, M Ferro… - Expert Review of …, 2019 - Taylor & Francis
Introduction: An altered metabolic regulation is involved in the development and progression
of different cancer types. As well as this, many genes associated with tumors are shown to …

Metabolic changes during prostate cancer development and progression

AMK Beier, M Puhr, MB Stope, C Thomas… - Journal of cancer …, 2023 - Springer
Metabolic reprogramming has been recognised as a hallmark in solid tumours. Malignant
modification of the tumour's bioenergetics provides energy for tumour growth and …

Comprehensive metabolomics and lipidomics profiling of prostate cancer tissue reveals metabolic dysregulations associated with disease development

AR Lima, M Carvalho, SS Aveiro, T Melo… - Journal of Proteome …, 2021 - ACS Publications
Prostate cancer (PCa) is a global health problem that affects millions of men every year. In
the past decade, metabolomics and related subareas, such as lipidomics, have …

[HTML][HTML] Personalized medicine for prostate cancer: is targeting metabolism a reality?

G Fidelito, MJ Watt, RA Taylor - Frontiers in Oncology, 2022 - frontiersin.org
Prostate cancer invokes major shifts in gene transcription and metabolic signaling to
mediate alterations in nutrient acquisition and metabolic substrate selection when compared …

Metabolic phenotyping in prostate cancer using multi-omics approaches

N Gómez-Cebrián, JL Poveda, A Pineda-Lucena… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer (PCa) is a hormone-dependent tumor characterized by a
highly heterogeneous clinical outcome. This neoplastic process has become a leading …