Several trace metals, including iron, copper, manganese and zinc are essential for normal
function of the nervous system. Both deficiency and excessive accumulation of these metals …

This short review will summarize the current knowledge on the uptake, storage, and export
of copper ions by astrocytes and will address the potential roles of astrocytes in copper …

With the industrial development and progressive increase in environmental pollution, the
mankind overexposure to heavy metals emerges as a pressing public health issue …

In the last two decades, there has been widespread acknowledgment of the pivotal role
played by astrocytes in diverse aspects of central nervous system functioning. Astrocytes are …

Copper is an essential element that is required for a variety of important cellular functions.
Since not only copper deficiency but also excess of copper can seriously affect cellular …

Copper is an essential trace element for many important cellular functions. However, excess
of copper can impair cellular functions by copper-induced oxidative stress. In brain …

Metal biology is receiving an unprecedented level of attention from the field of neuroscience.
As accumulating evidence continues to substantiate the essential function of metals in the …

Maintenance of ion gradient across the plasma membrane is of paramount importance for
neuronal physiology. The loss of control over these gradients may have severe …

Zinc is an essential dietary micronutrient that is abundant in the brain with diverse roles in
development, injury, and neurological diseases. With new imaging tools and chelators …

The brain is an organ that concentrates metals, and these metals are often localized to
astroglia. An examination of metal physiology of brain cells, particularly astroglia, offers …