Chinese medicinal herb Radix Astragali suppresses cardiac contractile dysfunction and inflammation in a rat model of autoimmune myocarditis

P Zhao, G Su, X Xiao, E Hao, X Zhu, J Ren - Toxicology letters, 2008 - Elsevier
Radix Astragali, a Chinese medicinal herb, consists of polysaccharides and flavonoids as its
main active ingredients. It has been widely used for treatment of cardiovascular diseases …

Resveratrol ameliorates experimental autoimmune myocarditis

Y Yoshida, T Shioi, T Izumi - Circulation Journal, 2007 - jstage.jst.go.jp
Background Myosin-induced autoimmune myocarditis of rats is a model of human dilated
cardiomyopathy. Resveratrol is a natural polyphenol found in grapes and wine that is …

Emodin, a naturally occurring anthraquinone, ameliorates experimental autoimmune myocarditis in rats

ZC Song, ZS Wang, JH Bai, Z Li, J Hu - The Tohoku journal of …, 2012 - jstage.jst.go.jp
Myocarditis is an inflammatory disease of the heart and a major cause of dilated
cardiomyopathy that can lead to heart failure and sudden death in young adults. Giant cell …

Curcumin ameliorates cardiac inflammation in rats with autoimmune myocarditis

S Mito, K Watanabe, M Harima… - Biological and …, 2011 - jstage.jst.go.jp
Curcuma longa. It is commonly used as a dietary spice and coloring agent in cooking, and is
used anecdotally as an herb in traditional Indian and Chinese medicine. It has been …

Myricetin ameliorates experimental autoimmune myocarditis in mice by modulating immune response and inhibiting MCP-1 expression

N Nie, Z Li, W Li, X Huang, Z Jiang, Y Shen - European journal of …, 2023 - Elsevier
Myocarditis is defined as an inflammatory disease of the myocardium, and the autoimmune
response specific to myocardium plays an important role in chronic myocarditis. Inhibiting …

[HTML][HTML] Ursolic acid reduces oxidative stress injury to ameliorate experimental autoimmune myocarditis by activating Nrf2/HO-1 signaling pathway

Y Fu, T Liu, S He, Y Zhang, Y Tan, Y Bai… - Frontiers in …, 2023 - frontiersin.org
Background: Oxidative stress is crucial in experimental autoimmune myocarditis (EAM)-
induced inflammatory myocardial injury. Ursolic acid (UA) is an antioxidant-enriched …

Natural products with anti-inflammatory and immunomodulatory activities against autoimmune myocarditis

B Javadi, A Sahebkar - Pharmacological research, 2017 - Elsevier
Myocarditis is an inflammatory disease of the myocardium associated with immune
dysfunction which may frequently lead to the development of dilated cardiomyopathy …

Crude Radix Aconiti Lateralis Preparata (Fuzi) with Glycyrrhiza Reduces Inflammation and Ventricular Remodeling in Mice through the TLR4/NF‐κB Pathway

P Yan, W Mao, L Jin, M Fang, X Liu… - Mediators of …, 2020 - Wiley Online Library
Radix Aconiti Lateralis Preparata (Fuzi) is a traditional Chinese medicine. Its alkaloids are
both cardiotonic and cardiotoxic; however, the underlying mechanisms are unclear …

Astragaloside IV attenuate MI-induced myocardial fibrosis and cardiac remodeling by inhibiting ROS/caspase-1/GSDMD signaling pathway

X Zhang, H Qu, T Yang, Q Liu, H Zhou - Cell Cycle, 2022 - Taylor & Francis
Astragalus membranaceus is a traditional Chinese medicine and has been widely used in
treating cardiovascular diseases (CVDs), such as asthma, edema, and chest tightness …

[HTML][HTML] Modulation of TLR4/NFκB Pathways in Autoimmune Myocarditis

L Interdonato, D Impellizzeri, R D'Amico, M Cordaro… - Antioxidants, 2023 - mdpi.com
Myocarditis is an inflammatory and oxidative disorder characterized by immune cell
recruitment in the damaged tissue and organ dysfunction. In this paper, we evaluated the …