Polydopamine nanoparticles as efficient scavengers for reactive oxygen species in periodontal disease

X Bao, J Zhao, J Sun, M Hu, X Yang - ACS nano, 2018 - ACS Publications
Antioxidative therapy has been considered an efficient strategy for the treatment of a series
of excessive reactive oxygen species (ROS)-triggered diseases, including oxidative-stress …

Polydopamine nanoparticles as dual-task platform for osteoarthritis therapy: A scavenger for reactive oxygen species and regulator for cellular powerhouses

X Wang, H Zhao, Z Liu, Y Wang, D Lin, L Chen… - Chemical Engineering …, 2021 - Elsevier
Because of the obscure etiology of osteoarthritis (OA) and unsatisfactory treatment
outcomes, new effective and minimally invasive therapies are urgently needed. Oxidative …

Cerium oxide nanozyme attenuates periodontal bone destruction by inhibiting the ROS–NFκB pathway

Y Yu, S Zhao, D Gu, B Zhu, H Liu, W Wu, J Wu, H Wei… - Nanoscale, 2022 - pubs.rsc.org
Periodontitis, an inflammatory disease of oxidative stress, occurs due to excess reactive
oxygen species (ROS) contributing to cell and tissue damage which in turn leads to alveolar …

ROS-scavenging nanomaterials to treat periodontitis

L Sui, J Wang, Z Xiao, Y Yang, Z Yang, K Ai - Frontiers in chemistry, 2020 - frontiersin.org
The incidence of periodontitis is very high, and up to 45–50% of people are suffering from
periodontitis. Periodontitis is caused by pathogens that invade teeth-supporting tissues such …

Cascade and ultrafast artificial antioxidases alleviate inflammation and bone resorption in periodontitis

Y Xie, S Xiao, L Huang, J Guo, M Bai, Y Gao, H Zhou… - ACS …, 2023 - ACS Publications
Periodontitis, one of the most common, challenging, and rapidly expanding oral diseases, is
an oxidative stress-related disease caused by excessive reactive oxygen species (ROS) …

Role of polydopamine's redox-activity on its pro-oxidant, radical-scavenging, and antimicrobial activities

H Liu, X Qu, H Tan, J Song, M Lei, E Kim, GF Payne… - Acta biomaterialia, 2019 - Elsevier
Polydopamine (PDA) is a bioinspired material and coating that offers diverse functional
activities (eg, photothermal, antioxidant, and antimicrobial) for a broad range of applications …

Catechol-Modified and MnO2-Nanozyme-Reinforced Hydrogel with Improved Antioxidant and Antibacterial Capacity for Periodontitis Treatment

S Hu, L Wang, J Li, D Li, H Zeng, T Chen… - ACS Biomaterials …, 2023 - ACS Publications
Periodontitis is an inflammatory disease characterized by tooth loss and alveolar bone
resorption. Bacteria are the original cause of periodontitis, and excess reactive oxygen …

Versatile hybrid nanoplatforms for treating periodontitis with chemical/photothermal therapy and reactive oxygen species scavenging

P Wang, L Wang, Y Zhan, Y Liu, Z Chen, J Xu… - Chemical Engineering …, 2023 - Elsevier
Given the limitations of clinical curettage for periodontitis, the thorough removal of dental
plaque at deep periodontal pockets and periodontal tissue repair require improvement with …

NIR-driven polydopamine-based nanoenzymes as ROS scavengers to suppress osteoarthritis progression

Y Chen, Y Wang, Z Chen, J Cai, K Li, H Huang… - Materials Today …, 2022 - Elsevier
The excessive reactive oxygen species (ROS) is always associated with the degradation of
cartilage matrix during osteoarthritis (OA). The development of novel nanoenzymes with …

Microenvironment-responsive metal-phenolic nanozyme release platform with antibacterial, ROS scavenging, and osteogenesis for periodontitis

Y Xu, Y Luo, Z Weng, H Xu, W Zhang, Q Li, H Liu… - ACS …, 2023 - ACS Publications
Periodontitis is a chronic inflammatory disease deriving from dental plaque, characterized by
the excessive accumulation of reactive oxygen species (ROS), matrix metalloproteinase …