Post-translational modification and regulation of actin

JR Terman, A Kashina - Current opinion in cell biology, 2013 - Elsevier
Many of the best-studied actin regulatory proteins use non-covalent means to modulate the
properties of actin. Yet, actin is also susceptible to covalent modifications of its amino acids …

Actin post-translational modifications: the cinderella of cytoskeletal control

S Varland, J Vandekerckhove, A Drazic - Trends in biochemical sciences, 2019 - cell.com
Actin is one of the most abundant proteins in eukaryotic cells and the main component of the
microfilament system. It plays essential roles in numerous cellular activities, including …

The makings of the 'actin code': regulation of actin's biological function at the amino acid and nucleotide level

P Vedula, A Kashina - Journal of cell science, 2018 - journals.biologists.com
The actin cytoskeleton plays key roles in every eukaryotic cell and is essential for cell
adhesion, migration, mechanosensing, and contractility in muscle and non-muscle tissues …

Mammalian actins: isoform-specific functions and diseases

C Ampe, M Van Troys - The Actin Cytoskeleton, 2017 - Springer
Actin is the central building block of the actin cytoskeleton, a highly regulated filamentous
network enabling dynamic processes of cells and simultaneously providing structure …

What we know and do not know about actin

TD Pollard - The actin cytoskeleton, 2017 - Springer
Seven decades of research have revealed much about actin structure, assembly, regulatory
proteins, and cellular functions. However, some key information is still missing, so we do not …

Actin-binding proteins: the long road to understanding the dynamic landscape of cellular actin networks

P Lappalainen - Molecular biology of the cell, 2016 - Am Soc Cell Biol
The actin cytoskeleton supports a vast number of cellular processes in nonmuscle cells. It is
well established that the organization and dynamics of the actin cytoskeleton are controlled …

Conformational dynamics of actin: effectors and implications for biological function

G Hild, B Bugyi, M Nyitrai - Cytoskeleton, 2010 - Wiley Online Library
Actin is a protein abundant in many cell types. Decades of investigations have provided
evidence that it has many functions in living cells. The diverse morphology and dynamics of …

A solution to the long-standing problem of actin expression and purification

RH Ceron, PJ Carman, G Rebowski… - Proceedings of the …, 2022 - National Acad Sciences
Actin is the most abundant protein in the cytoplasm of eukaryotic cells and interacts with
hundreds of proteins to perform essential functions, including cell motility and cytokinesis …

[HTML][HTML] Oxidation and reduction of actin: Origin, impact in vitro and functional consequences in vivo

C Rouyère, T Serrano, S Frémont, A Echard - European journal of cell …, 2022 - Elsevier
Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …

Actin structure and function

R Dominguez, KC Holmes - Annual review of biophysics, 2011 - annualreviews.org
Actin is the most abundant protein in most eukaryotic cells. It is highly conserved and
participates in more protein-protein interactions than any known protein. These properties …