Host Transmission of Salmonella enterica Serovar Typhimurium Is Controlled by Virulence Factors and Indigenous Intestinal Microbiota

TD Lawley, DM Bouley, YE Hoy, C Gerke… - Infection and …, 2008 - Am Soc Microbiol
Transmission is an essential stage of a pathogen's life cycle and remains poorly understood.
We describe here a model in which persistently infected 129X1/SvJ mice provide a natural …

Enteric salmonellosis disrupts the microbial ecology of the murine gastrointestinal tract

M Barman, D Unold, K Shifley, E Amir… - Infection and …, 2008 - Am Soc Microbiol
The commensal microbiota protects the murine host from enteric pathogens. Nevertheless,
specific pathogens are able to colonize the intestinal tract and invade, despite the presence …

[HTML][HTML] Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

B Stecher, R Robbiani, AW Walker, AM Westendorf… - PLoS …, 2007 - journals.plos.org
Most mucosal surfaces of the mammalian body are colonized by microbial communities
(“microbiota”). A high density of commensal microbiota inhabits the intestine and shields …

[HTML][HTML] The Intestinal Microbiota Plays a Role in Salmonella-Induced Colitis Independent of Pathogen Colonization

RBR Ferreira, N Gill, BP Willing, LCM Antunes… - PloS one, 2011 - journals.plos.org
The intestinal microbiota is composed of hundreds of species of bacteria, fungi and protozoa
and is critical for numerous biological processes, such as nutrient acquisition, vitamin …

Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection

I Sekirov, NM Tam, M Jogova, ML Robertson… - Infection and …, 2008 - Am Soc Microbiol
Intestinal microbiota comprises microbial communities that reside in the gastrointestinal tract
and are critical to normal host physiology. Understanding the microbiota's role in host …

[HTML][HTML] Interaction of Salmonella spp. with the Intestinal Microbiota

BMM Ahmer, JS Gunn - Frontiers in microbiology, 2011 - frontiersin.org
Salmonella spp. are major cause of human morbidity and mortality worldwide. Upon entry
into the human host, Salmonella spp. must overcome the resistance to colonization …

[HTML][HTML] Salmonella enterica Serovar Typhimurium Exploits Inflammation to Modify Swine Intestinal Microbiota

R Drumo, M Pesciaroli, J Ruggeri… - Frontiers in cellular …, 2016 - frontiersin.org
Salmonella enterica serovar Typhimurium is an important zoonotic gastrointestinal pathogen
responsible for foodborne disease worldwide. It is a successful enteric pathogen because it …

Salmonella enterica Serovar Typhimurium Pathogenicity Island 2 Is Necessary for Complete Virulence in a Mouse Model of Infectious Enterocolitis

B Coburn, Y Li, D Owen, BA Vallance… - Infection and …, 2005 - Am Soc Microbiol
Salmonella species cause a wide range of disease in multiple hosts. Salmonella enterica
serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid …

[HTML][HTML] Intraspecies Competition for Niches in the Distal Gut Dictate Transmission during Persistent Salmonella Infection

LH Lam, DM Monack - PLoS pathogens, 2014 - journals.plos.org
In order to be transmitted, a pathogen must first successfully colonize and multiply within a
host. Ecological principles can be applied to study host-pathogen interactions to predict …

The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune …

P Kaiser, M Diard, B Stecher… - Immunological reviews, 2012 - Wiley Online Library
The mammalian intestine is colonized by a dense microbial community, the microbiota.
Homeostatic and symbiotic interactions facilitate the peaceful co‐existence between the …