Host Transmission of Salmonella enterica Serovar Typhimurium Is Controlled by Virulence Factors and Indigenous Intestinal Microbiota
TD Lawley, DM Bouley, YE Hoy, C Gerke… - Infection and …, 2008 - Am Soc Microbiol
Transmission is an essential stage of a pathogen's life cycle and remains poorly understood.
We describe here a model in which persistently infected 129X1/SvJ mice provide a natural …
We describe here a model in which persistently infected 129X1/SvJ mice provide a natural …
Enteric salmonellosis disrupts the microbial ecology of the murine gastrointestinal tract
M Barman, D Unold, K Shifley, E Amir… - Infection and …, 2008 - Am Soc Microbiol
The commensal microbiota protects the murine host from enteric pathogens. Nevertheless,
specific pathogens are able to colonize the intestinal tract and invade, despite the presence …
specific pathogens are able to colonize the intestinal tract and invade, despite the presence …
[HTML][HTML] Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota
Most mucosal surfaces of the mammalian body are colonized by microbial communities
(“microbiota”). A high density of commensal microbiota inhabits the intestine and shields …
(“microbiota”). A high density of commensal microbiota inhabits the intestine and shields …
[HTML][HTML] The Intestinal Microbiota Plays a Role in Salmonella-Induced Colitis Independent of Pathogen Colonization
The intestinal microbiota is composed of hundreds of species of bacteria, fungi and protozoa
and is critical for numerous biological processes, such as nutrient acquisition, vitamin …
and is critical for numerous biological processes, such as nutrient acquisition, vitamin …
Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection
I Sekirov, NM Tam, M Jogova, ML Robertson… - Infection and …, 2008 - Am Soc Microbiol
Intestinal microbiota comprises microbial communities that reside in the gastrointestinal tract
and are critical to normal host physiology. Understanding the microbiota's role in host …
and are critical to normal host physiology. Understanding the microbiota's role in host …
[HTML][HTML] Interaction of Salmonella spp. with the Intestinal Microbiota
BMM Ahmer, JS Gunn - Frontiers in microbiology, 2011 - frontiersin.org
Salmonella spp. are major cause of human morbidity and mortality worldwide. Upon entry
into the human host, Salmonella spp. must overcome the resistance to colonization …
into the human host, Salmonella spp. must overcome the resistance to colonization …
[HTML][HTML] Salmonella enterica Serovar Typhimurium Exploits Inflammation to Modify Swine Intestinal Microbiota
R Drumo, M Pesciaroli, J Ruggeri… - Frontiers in cellular …, 2016 - frontiersin.org
Salmonella enterica serovar Typhimurium is an important zoonotic gastrointestinal pathogen
responsible for foodborne disease worldwide. It is a successful enteric pathogen because it …
responsible for foodborne disease worldwide. It is a successful enteric pathogen because it …
Salmonella enterica Serovar Typhimurium Pathogenicity Island 2 Is Necessary for Complete Virulence in a Mouse Model of Infectious Enterocolitis
B Coburn, Y Li, D Owen, BA Vallance… - Infection and …, 2005 - Am Soc Microbiol
Salmonella species cause a wide range of disease in multiple hosts. Salmonella enterica
serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid …
serovar Typhimurium causes self-limited intestinal disease in humans and systemic typhoid …
[HTML][HTML] Intraspecies Competition for Niches in the Distal Gut Dictate Transmission during Persistent Salmonella Infection
LH Lam, DM Monack - PLoS pathogens, 2014 - journals.plos.org
In order to be transmitted, a pathogen must first successfully colonize and multiply within a
host. Ecological principles can be applied to study host-pathogen interactions to predict …
host. Ecological principles can be applied to study host-pathogen interactions to predict …
The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune …
The mammalian intestine is colonized by a dense microbial community, the microbiota.
Homeostatic and symbiotic interactions facilitate the peaceful co‐existence between the …
Homeostatic and symbiotic interactions facilitate the peaceful co‐existence between the …
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- functional analysis virulence factors