Healthy individuals can harbour microscopic tumours and dysplastic foci in different organs
in an undetectable and asymptomatic state for many years. These lesions do not progress in …

Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

The recognition that angiogenesis is a key early event in tumor progression and metastasis
has led to the development of new strategies for cancer therapy. The generation of a new …

The potential to block tumor growth by inhibition of the neoangiogenic process represents
an intriguing approach to the treatment of solid tumors. The high proliferation rate in the …

A number of anti-angiogenesis drugs have been FDA-approved and are being used in
cancer treatment, and a number of other agents are in different stages of clinical …

Angiogenesis is a vital process resulting in the formation of new blood vessels. It is normally
a highly regulated process that occurs during human development, reproduction, and …

Formation of new blood vessels in tumors, a process termed tumor angiogenesis, is a crucial
step during oncogenic progression. Blocking tumor angiogenesis is therefore expected to …

Angiogenesis plays an important role in the development of cancer since it allows for the
delivery of oxygen, nutrients, and growth factors as well as tumor dissemination to distant …

Angiogenesis, the formation of new blood vessels from existing vasculature, is essential to
the late stages of carcinogenesis, allowing tumours to grow beyond 1–2 mm in diameter …

Angiogenesis is a term that describes the formation of new blood and lymphatic vessels from
a pre-existing vasculature. This allows tumour cells to acquire sustenance in the form of …