Long noncoding RNA ANRIL promotes non–small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression

F Nie, M Sun, J Yang, M Xie, T Xu, R Xia, Y Liu… - Molecular cancer …, 2015 - AACR
Recent evidence highlights long noncoding RNAs (lncRNA) as crucial regulators of cancer
biology that contribute to essential cancer cell functions such as cell proliferation, apoptosis …

Long noncoding RNA ANRIL could be transactivated by c-Myc and promote tumor progression of non-small-cell lung cancer

Y Lu, X Zhou, L Xu, C Rong, C Shen… - OncoTargets and …, 2016 - Taylor & Francis
In recent years, long noncoding RNAs (lncRNAs) have been demonstrated to play important
roles in the development of human cancer. We assessed the role of lncRNA ANRIL in non …

[HTML][HTML] Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2

M Huang, W Chen, F Qi, R Xia, M Sun, T Xu… - Journal of hematology & …, 2015 - Springer
Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
death, especially in China. And the mechanism of its progression remains poorly …

[HTML][HTML] Increased expression of the long non-coding RNA ANRIL promotes lung cancer cell metastasis and correlates with poor prognosis

L Lin, ZT Gu, WH Chen, KJ Cao - Diagnostic pathology, 2015 - Springer
Background Emerging evidences indicate that dysregulated long non-coding RNAs
(lncRNAs) are implicated in cancer tumorigenesis and progression. LncRNA ANRIL has …

[HTML][HTML] LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose …

ZW Zou, C Ma, L Medoro, L Chen, B Wang, R Gupta… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long noncoding RNAs play a vital role in diverse biological processes such as embryonic
development, cell growth, and tumorigenesis. In this study, we report that LncRNA ANRIL …

Long non-coding RNA ANRIL indicates a poor prognosis of cervical cancer and promotes carcinogenesis via PI3K/Akt pathways

D Zhang, G Sun, H Zhang, J Tian, Y Li - Biomedicine & pharmacotherapy, 2017 - Elsevier
Accumulating evidence suggests that long non-coding RNAs (lncRNAs) are playing critical
roles in tumorgenesis. LncRNA ANRIL has been reported to promote tumor progression in …

[HTML][HTML] Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a

E Zhang, R Kong, D Yin, L You, M Sun, L Han, T Xu… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Long noncoding RNAs are involved in diseases including cancer. Here, we reported that
ANRIL (CDKN2B-AS1), a 3.8-kb long noncoding RNA, recruiting and binding to PRC2, was …

Long noncoding RNA ANRIL regulates proliferation of non-small cell lung cancer and cervical cancer cells

M Naemura, C Murasaki, Y Inoue, H Okamoto… - Anticancer …, 2015 - ar.iiarjournals.org
Background: Long noncoding RNA ANRIL (antisense non-coding RNA in the INK4 locus)
represses p15 and p16, which induce cell-cycle arrest at G1 phase, leading to enhanced …

ANRIL: a pivotal tumor suppressor long non-coding RNA in human cancers

Z Li, X Yu, J Shen - Tumor Biology, 2016 - Springer
Long non-coding RNAs (lncRNAs) are a family of non-protein-coding RNAs with length
more than 200 nucleotides. LncRNAs played important roles in many biological processes …

Long non-coding RNA ANRIL is up-regulated in bladder cancer and regulates bladder cancer cell proliferation and apoptosis through the intrinsic pathway

H Zhu, X Li, Y Song, P Zhang, Y Xiao, Y Xing - … and biophysical research …, 2015 - Elsevier
Antisense non-coding RNA in the INK4 locus (ANRIL) is a member of long non-coding RNAs
and has been reported to be dysregulated in several human cancers. However, the role of …