Prostate cancer (PCa) is globally the second most diagnosed cancer type and the most
common cause of cancer-related deaths in men. Family history of PCa, hereditary breast …

Prostate cancer (PrCa) ranks among the top five cancers for both incidence and mortality
worldwide. A significant proportion of PrCa susceptibility has been attributed to inherited …

Prostate cancer is the most commonly diagnosed cancer among men in the United States as
well as most Western countries. A significant proportion of men report having a positive …

A significant proportion of prostate cancer diagnoses may be associated with a strong
hereditary component. Men who have multiple single‐gene polymorphisms and a family …

It is increasingly important for clinicians involved in the management of prostate cancer to
understand the relevance of heritable (germline) mutations that, for select patients, affect …

Purpose: Until recently the role of germline genetics in prostate cancer care was not well
defined. While important questions remain, we reviewed the current understanding of …

Purpose Guidelines are limited for genetic testing for prostate cancer (PCA). The goal of this
conference was to develop an expert consensus-driven working framework for …

Purpose: Increased prostate cancer risk has been reported for BRCA mutation carriers, but
BRCA-associated clinicopathologic features have not been clearly defined. Experimental …

CONTEXT: Despite widespread screening for prostate cancer (PCa) and major advances in
the treatment of metastatic disease, PCa remains the second most common cause of cancer …

Prostate cancer ranks fifth in cancer-related mortality in men worldwide. DNA damage is
implicated in cancer and DNA damage response (DDR) pathways are in place against this …