[HTML][HTML] Observations on the ex situ perfusion of livers for transplantation
CJE Watson, V Kosmoliaptsis, C Pley, L Randle… - American journal of …, 2018 - Elsevier
Normothermic ex situ liver perfusion might allow viability assessment of livers before
transplantation. Perfusion characteristics were studied in 47 liver perfusions, of which 22 …
transplantation. Perfusion characteristics were studied in 47 liver perfusions, of which 22 …
Normothermic perfusion in the assessment and preservation of declined livers before transplantation: hyperoxia and vasoplegia—important lessons from the first 12 …
CJE Watson, V Kosmoliaptsis, LV Randle… - …, 2017 - journals.lww.com
Background A program of normothermic ex situ liver perfusion (NESLiP) was developed to
facilitate better assessment and use of marginal livers, while minimizing cold ischemia …
facilitate better assessment and use of marginal livers, while minimizing cold ischemia …
[HTML][HTML] Preimplant normothermic liver perfusion of a suboptimal liver donated after circulatory death
CJE Watson, V Kosmoliaptsis, LV Randle… - American Journal of …, 2016 - Elsevier
Livers retrieved after circulatory death are associated with an increased incidence of primary
nonfunction, early allograft dysfunction, and biliary strictures. The authors report a case of …
nonfunction, early allograft dysfunction, and biliary strictures. The authors report a case of …
Predicting early allograft function after normothermic machine perfusion
CJE Watson, R Gaurav, C Fear, L Swift, L Selves… - …, 2022 - journals.lww.com
Background. Normothermic ex situ liver perfusion is increasingly used to assess donor
livers, but there remains a paucity of evidence regarding criteria upon which to base a …
livers, but there remains a paucity of evidence regarding criteria upon which to base a …
From “gut feeling” to objectivity: machine preservation of the liver as a tool to assess organ viability
CJE Watson, I Jochmans - Current transplantation reports, 2018 - Springer
Abstract Purpose of Review The purpose of this review was to summarise how machine
perfusion could contribute to viability assessment of donor livers. Recent Findings In both …
perfusion could contribute to viability assessment of donor livers. Recent Findings In both …
Ex vivo Normothermic Machine Perfusion and Viability Testing of Discarded Human Donor Livers
S Op den Dries, N Karimian, ME Sutton… - American Journal of …, 2013 - Wiley Online Library
In contrast to traditional static cold preservation of donor livers, normothermic machine
perfusion may reduce preservation injury, improve graft viability and potentially allows ex …
perfusion may reduce preservation injury, improve graft viability and potentially allows ex …
Transplantation of declined livers after normothermic perfusion
C Quintini, L Del Prete, A Simioni, L Del Angel, TD Uso… - Surgery, 2022 - Elsevier
Background The persistent shortage of liver allografts contributes to significant waitlist
mortality despite efforts to increase organ donation. Normothermic machine perfusion holds …
mortality despite efforts to increase organ donation. Normothermic machine perfusion holds …
Transplantation of Declined Liver Allografts Following Normothermic Ex‐Situ Evaluation
H Mergental, M Perera, RW Laing… - American journal of …, 2016 - Wiley Online Library
The demand for liver transplantation (LT) exceeds supply, with rising waiting list mortality.
Utilization of high‐risk organs is low and a substantial number of procured livers are …
Utilization of high‐risk organs is low and a substantial number of procured livers are …
Criteria for Viability Assessment of Discarded Human Donor Livers during Ex Vivo Normothermic Machine Perfusion
ME Sutton, S op den Dries, N Karimian, PD Weeder… - PloS one, 2014 - journals.plos.org
Although normothermic machine perfusion of donor livers may allow assessment of graft
viability prior to transplantation, there are currently no data on what would be a good …
viability prior to transplantation, there are currently no data on what would be a good …
Biliary bicarbonate, pH, and glucose are suitable biomarkers of biliary viability during ex situ normothermic machine perfusion of human donor livers
APM Matton, Y de Vries, LC Burlage, R van Rijn… - …, 2019 - journals.lww.com
Background. Ex situ normothermic machine perfusion (NMP) can be used to assess viability
of suboptimal donor livers before implantation. Our aim was to assess the diagnostic …
of suboptimal donor livers before implantation. Our aim was to assess the diagnostic …