The interaction of cells within their microenvironmental niche is fundamental to cell
migration, positioning, growth and differentiation in order to form and maintain complex …

Second harmonic generation (SHG) and third harmonic generation (THG) microscopies
have emerged as powerful imaging modalities to examine structural properties of a wide …

Second-harmonic generation (SHG) microscopy began to emerge as a high-resolution
optical imaging modality in the late 1990s, about 10 years after two-photon excited …

We find that several key endogenous protein structures give rise to intense second-
harmonic generation (SHG)—nonabsorptive frequency doubling of an excitation laser line …

Multiphoton microscopy has become a standard method for noninvasive imaging of thick
specimens with subcellular resolution. Higher harmonic generation microscopy (HHGM) …

Second and Third Harmonic Generation (SHG and THG) microscopy is based on optical
effects which are induced by specific inherent physical properties of a specimen. As a multi …

Lipid bodies have an important role in energy storage and lipid regulation. Here we show
that lipid bodies are a major source of contrast in third-harmonic generation (THG) …

In this work we aim to show how it is possible to exploit the second harmonic generation
(SHG) signal for producing multimodal microscopic images of biological tissues. SHG …

Third-harmonic generation (THG) microscopy provides images of unstained biological
samples based on spatial variations in third-order nonlinear susceptibility, refractive index …

The last 30 years has seen great advances in optical microscopy with the introduction of
sophisticated fluorescence-based imaging methods such as confocal and multiphoton laser …