Digoxin remains an important therapeutic option for the outpatient management of patients
with chronic symptomatic heart failure caused by systolic dysfunction. Randomized control …

Digoxin is the oldest cardiac drug still in contemporary use, yet its role in the management of
patients with heart failure (HF) remains controversial. A purified cardiac glycoside derived …

Although two centuries of anecdotal clinical evidence support the use of cardiac glycosides
for the treatment of heart failure, controversy has surrounded their efficacy and appropriate …

Although digitalis glycosides were introduced in the treatment of cardiac maladies> 200
years ago, controversy persists regarding the precise role of digoxin in any multidrug …

To assess the efficacy of digitalis in patients with chronic clinically compensated congestive
heart failure and normal sinus rhythm, we performed a double-blind crossover study with …

Clinical studies have solidified the utility of digoxin in patients with left ventricular dysfunction
and normal sinus rhythm. No definitive data have been published to clarify the range of …

Digitalis preparations have been used for centuries. Digoxin is an agent that is readily
available, can be administered acutely and long-term, intravenously or orally, is safe and …

Digitalis preparations have been used therapeutically for thousands of years. 1 The first
detailed description of digitalis was made by Withering in 1785, who noted that the drug …

Although supported by 2 centuries of anecdotal clinical evidence, the safely and efficacy of
the cardiac glycosides for the treatment of congestive heart due to systolic ventricular …

Digitalis is the oldest compound in cardiovascular medicine that continues to be used in
contemporary clinical practice. 1 Evidence supporting the beneficial effects of digoxin on …