The aim of this study was to explore the potential of a new selective serotonin transporter (5‐
HTT) inhibitor, N, N‐dimethyl‐2‐(2‐amino‐4‐methylphenylthio) benzylamine (MADAM, Ki …

11C-N, N-Dimethyl-2-(2-amino-4-methylphenylthio) benzylamine (11C-MADAM) is a newly
synthesized radioligand with high selectivity and specificity for the serotonin transporter (5 …

Abstract [11C] MADAM, or [11C] N, N‐dimethyl‐2‐(2‐amino‐4‐methylphenyl thio)
benzylamine, is a radioligand suitable for positron emission tomography (PET) studies of the …

There has been considerable interest in the development of PET radioligands that are useful
for imaging serotonin transporter (SERT) in the living human brain. For the last decade, 11C …

N, N-Dimethyl-2-(2-amino-4-methylthiophenylthio) benzylamine (SMe-ADAM, 1) is a highly
potent and selective inhibitor of the serotonin transporter (SERT). This compound was …

Carbon-11-labeled N, N-dimethyl-2-(2′-amino-4′-hydroxymethylphenylthio) benzylamine
(HOMADAM) was synthesized as a new serotonin transporter (SERT) imaging agent …

There has been considerable interest in the development of a PET radioligand selective for
the serotonin (5-hydroxytryptamine [5-HT]) transporter (SERT) that can be used to image 5 …

Alterations of serotonin transporters (SERT) are implicated in a large number of psychiatric
conditions. 11C-(+)-6β-(4-Methylthiophenyl)-1, 2, 3, 5, 6α, 10β-hexahydropyrrolo [2, 1-a] …

A new PET radioligand for the serotonin transporter (SERT),[11C]-5-bromo-2-[2-(
dimethylaminomethylphenylsulfanyl)] phenylamine ([11C] DAPA (10), was synthesized and …

The synthesis, radiolabeling, and in vitro and in vivo evaluation of a new positron emission
tomography (PET) radioligand for the serotonin transporter (SERT),[11C] 2-[2 …