Human T cell response to dengue virus infection
DENV is a major public health problem worldwide, thus underlining the overall significance
of the proposed Program. The four dengue virus (DENV) serotypes (1–4) cause the most …
of the proposed Program. The four dengue virus (DENV) serotypes (1–4) cause the most …
CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination
LE Yauch, TR Prestwood, MM May… - The Journal of …, 2010 - journals.aai.org
The contribution of T cells to the host response to dengue virus (DENV) infection is not well
understood. We previously demonstrated a protective role for CD8+ T cells during primary …
understood. We previously demonstrated a protective role for CD8+ T cells during primary …
A protective role for dengue virus-specific CD8+ T cells
LE Yauch, RM Zellweger, MF Kotturi… - The Journal of …, 2009 - journals.aai.org
Infection with one of the four serotypes of dengue virus (DENV1–4) can result in a range of
clinical manifestations in humans, from dengue fever to the more serious dengue …
clinical manifestations in humans, from dengue fever to the more serious dengue …
T-cell immunity to infection with dengue virus in humans
D Weiskopf, A Sette - Frontiers in immunology, 2014 - frontiersin.org
Dengue virus (DENV) is the etiologic agent of dengue fever, the most significant mosquito-
borne viral disease in humans. Up to 400 million DENV infections occur every year, and …
borne viral disease in humans. Up to 400 million DENV infections occur every year, and …
Protective role of cross-reactive CD8 T cells against dengue virus infection
Infection with one of the four dengue virus serotypes (DENV1-4) presumably leads to
lifelong immunity against the infecting serotype but not against heterotypic reinfection …
lifelong immunity against the infecting serotype but not against heterotypic reinfection …
Characterization of human CD8 T cell responses in dengue virus-infected patients from India
A Chandele, J Sewatanon, S Gunisetty… - Journal of …, 2016 - Am Soc Microbiol
Epidemiological studies suggest that India has the largest number of dengue virus infection
cases worldwide. However, there is minimal information about the immunological responses …
cases worldwide. However, there is minimal information about the immunological responses …
Cytotoxic CD4 T cells: differentiation, function, and application to dengue virus infection
Dengue virus (DENV) has spread through most tropical and subtropical areas of the world
and represents a serious public health problem. The control of DENV infection has not yet …
and represents a serious public health problem. The control of DENV infection has not yet …
Differential Targeting of Viral Components by CD4+ versus CD8+ T Lymphocytes in Dengue Virus Infection
L Rivino, EAP Kumaran, V Jovanovic, K Nadua… - Journal of …, 2013 - Am Soc Microbiol
Dengue virus (DENV) is the principal arthropod-borne viral pathogen afflicting human
populations. While repertoires of antibodies to DENV have been linked to protection or …
populations. While repertoires of antibodies to DENV have been linked to protection or …
Altered cytokine responses of dengue-specific CD4+ T cells to heterologous serotypes
MM Mangada, AL Rothman - The Journal of Immunology, 2005 - journals.aai.org
The interplay of different inflammatory cytokines induced during a dengue (DEN) virus
infection plays a role in either protection or increased disease severity. We measured the …
infection plays a role in either protection or increased disease severity. We measured the …
Multiple specificities in the murine CD4+ and CD8+ T-cell response to dengue virus
AL Rothman, I Kurane, FA Ennis - Journal of virology, 1996 - Am Soc Microbiol
The target epitopes, serotype specificity, and cytolytic function of dengue virus-specific T
cells may influence their theoretical roles in protection against secondary infection as well as …
cells may influence their theoretical roles in protection against secondary infection as well as …