Deployment of drug-eluting stents instead of bare-metal stents has dramatically reduced
restenosis rates, but rates of very late stent thrombosis (> 1 year postimplantation) have …

Coronary artery stenting following balloon angioplasty represents the gold standard in
revascularization of coronary artery stenoses. However, stent deployment as well as …

Plaque rupture, usually of a precursor lesion known as a'vulnerable plaque'or'thin-cap
fibroatheroma', is the leading cause of thrombosis. Less-frequent aetiologies of coronary …

Background—Despite the increasing use of stents, few reports have described human
coronary artery morphology early and late after stenting. Methods and Results—Histology …

Restenosis and thrombosis are potentially fatal complications of coronary stenting with a
recognized multifactorial etiology. The effect of documented risk factors, however, cannot …

Modern-day stenting procedures leverage advances in pharmacotherapy and device
innovation. Patients treated with contemporary antiplatelet agents, peri-procedural …

At present, 90 to 95 percent of percutaneous coronary interventions involve the implantation
of a stent, often a drug-eluting stent, though most published data originated in the era of bare …

Endothelial cells form a continuous syncytium that separates the intravascular and
extravascular space. The endothelium is a selectively permeable and metabolically active …

Although rare, stent thrombosis remains a severe complication after stent implantation owing
to its high morbidity and mortality. Since the introduction of drug-eluting stents (DES), most …

Drug eluting stents (DES) have expanded the use of stents for the treatment of coronary
atherosclerotic disease with significant reduction in restenosis rates. However, DES have …