In the past 10 yeats, it has been clearly shown that vasoactive substances reduce portal
pressure in patients or animals with portal hypertension. Some of these substances act by …

Drug therapy for acute variceal bleeding should be viewed as an adjunct to emergency
sclerotherapy. Its role in preventing very early rebleeding (within days) following …

T treatment of portal hyper-tension consists of reducing portal
pressure, and thus variceal pressure and wall tension, to decrease the risk of or to treat …

Certain vasoactive substances reduce portal pressure in patients or animals with portal
hypertension by either inducing splanchnic vasoconstriction or reducing hepatic vascular …

Pharmacology of portal hypertension is a very active area. Several vasoactive agents are
now known to reduce portal pressure (Fig. 1; Table 1) and, therefore, are potentially useful in …

Portal hypertension is a common syndrome, usually caused by liver disease, that is
characterized by a pathological increase of the portal venous pressure. Blood pressure in …

The continuous oral administration of different drugs can produce a sustained reduction in
portal pressure in patients with portal hypertension. β-Adrenergic antagonists, α 2 …

The pathogenesis of portal hypertension remains poorly understood. Similarly,
pharmacological manipulation for the prevention and treatment of variceal haemorrhage has …

Variceal formation and rupture are dreaded complications of chronic liver disease and portal
hypertension. The pharmacologic treatment of portal hypertension should be able to stop as …

Interest in the pathophysiology and management of portal hypertension has increased
exponen-tially over the last 25 years, from modest begin-nings to an almost explosion of …