ABCG2 is an ATP-binding cassette (ABC) transporter that protects tissues against
xenobiotics, affects the pharmacokinetics of drugs and contributes to multidrug resistance …

ABCG2 is an ATP-binding cassette (ABC) transporter whose function affects the
pharmacokinetics of drugs and contributes to multidrug resistance of cancer cells. While its …

ABCG2 is an ATP binding cassette (ABC) half-transporter that plays a key role in multidrug
resistance to chemotherapy. ABCG2 is believed to be a functional homodimer that has been …

ABCG2 is a multidrug efflux pump associated with resistance of cancer cells to a plethora of
unrelated drugs. ABCG2 is a" half-transporter," and previous studies have indicated that it …

ABCG2 is an ATP-binding cassette (ABC) transporter that extrudes a wide range of
xenobiotics and drugs from the cell and contributes to multidrug resistance in cancer cells …

ABCG2 is a constitutively expressed ATP-binding cassette (ABC) transporter that protects
many tissues against xenobiotic molecules. Its activity affects the pharmacokinetics of …

ABCB1 detoxifies cells by exporting diverse xenobiotic compounds, thereby limiting drug
disposition and contributing to multidrug resistance in cancer cells. Multiple small-molecule …

ABCG2 is an ABC transporter that extrudes a variety of compounds from cells, and presents
an obstacle in treating chemotherapy-resistant cancers. Despite recent structural insights, no …

ABCG2 was discovered in multi-drug-resistant cancer cells, with the identification of
chemotherapeutic agents, such as mitoxantrone, flavopiridol, methotrexate and irinotecan as …

The ABCG2 protein has a key role in the transport of a wide range of structurally dissimilar
endo‐and xenobiotics in the human body, especially in the tissue barriers and the …