Oxidative stress markers and apoptosis in the prostate of diabetic rats and the influence of vitamin C treatment

MG Gobbo, DL Ribeiro, SR Taboga… - Journal of Cellular …, 2012 - Wiley Online Library
Negative consequences of diabetes on the prostate such as involution are associated with
diminished testosterone, insulin deficiency, and hyperglycemia. The contributions of …

Testicular oxidative damage and role of combined antioxidant supplementation in experimental diabetic rats

M Mohasseb, S Ebied, MAH Yehia… - Journal of physiology and …, 2011 - Springer
The present study was designated to assess oxidative damage and its effect on germ cell
apoptosis in testes of streptozotocin (STZ)-induced diabetic rats. The role of antioxidant …

Age-related changes in rat prostate tissue; perspective of protein oxidation

D Uzun, K Yanar, P Atukeren, T Cebe, M Mengi… - The Aging …, 2015 - Taylor & Francis
Background: Increased systemic oxidative stress is considered as an important risk factor for
prostate cancer occurrence; however, the relationship between impaired redox homeostasis …

[HTML][HTML] Protective effect of vitamin E on oxidative stress and sperm apoptosis in diabetic Mice

KM Khorramabadi, AR Talebi… - International Journal …, 2019 - ncbi.nlm.nih.gov
Background Generation of free radicals and oxidative stress are a major contributor to
diabetes. These factors lead to the development of diabetic testicles disorders. Objective In …

The protective effect of metformin against testicular damage in diabetes and prostate cancer model

P Koroglu Aydın, O Karabulut‐Bulan… - Cell Biochemistry …, 2022 - Wiley Online Library
Individuals with diabetes have an increased risk of breast, colorectal, pancreatic and
prostate cancer. Metformin, an oral biguanide used to treat diabetes, has anti …

[DOC][DOC] Effects of oxidative stress induced by streptozotocin on the morphology and trace minerals of the testes of diabetic wistar rats

SO Adewole, EA Caxton-Martins… - …, 2007 - pharmacologyonline.silae.it
ABSTRACT A considerable amount of clinical and experimental evidence now exists
suggesting that many biochemical pathways strictly associated with diabetes increase the …

[HTML][HTML] The effects of diabetes mellitus, age, and vitamin E on testicular oxidative stress

H Aybek, Z Aybek, S Rota, N Şen, M Akbulut - Fertility and sterility, 2008 - Elsevier
OBJECTIVE: To examine the effects of age and/or diabetes on oxidative stress and
steroidogenesis, and the protective effect of vitamin E in testis tissue. DESIGN: Controlled …

Resveratrol alleviates diabetes-induced testicular dysfunction by inhibiting oxidative stress and c-Jun N-terminal kinase signaling in rats

I Faid, H Al-Hussaini, N Kilarkaje - Toxicology and Applied Pharmacology, 2015 - Elsevier
Diabetes adversely affects reproductive functions in humans and animals. The present study
investigated the effects of Resveratrol on diabetes-induced alterations in oxidative stress, c …

Diabetes-induced testicular oxidative stress, inflammation, and caspase-dependent apoptosis: the protective role of metformin

VU Nna, ABA Bakar, A Ahmad… - Archives of physiology …, 2020 - Taylor & Francis
Context: Metformin's effect on glycaemic control is well documented, but its effect on
diabetes-induced testicular impairment has been scarcely reported. Objective: To …

Effects of ascorbic acid on spermatogenesis and sperm parameters in diabetic rats

MV Aguirre-Arias, V Velarde, RD Moreno - Cell and tissue research, 2017 - Springer
Diabetes mellitus in human and animal models has been correlated with low sperm count,
testicular abnormalities, high levels of germ cell death, and oxidative stress. In this study, we …