Traditional Chinese medicine reverses cancer multidrug resistance and its mechanism

J Wei, Z Liu, J He, Q Liu, Y Lu, S He, B Yuan… - Clinical and …, 2022 - Springer
Chemotherapy is one of the most commonly used clinical treatments among the currently
available cancer therapies. However, the phenomenon of Multidrug resistance (MDR) has …

[HTML][HTML] Effect of traditional Chinese medicine components on multidrug resistance in tumors mediated by P-glycoprotein

X Xia, SPC Cole, T Cai, Y Cai - Oncology letters, 2017 - spandidos-publications.com
Multidrug resistance (MDR) is a major cause of chemotherapy failure. It occurs when an
organism is resistant to one type of drug, but also develops resistance to other drugs with …

Research progress on reversing multidrug resistance in tumors by using Chinese medicine

H Zhao, H Xie, J Li, C Ren, Y Chen - Chinese journal of integrative …, 2018 - Springer
Multidrug resistance (MDR) is a major cause of cancer chemotherapy failure, and it is
important to develop suitable reversal agents to overcome MDR. A majority of chemical …

Multidrug resistance of gastric cancer: The mechanisms and Chinese medicine reversal agents

WJ Huang, S Ruan, F Wen, X Lu, S Gu… - Cancer management …, 2020 - Taylor & Francis
Chemotherapy is the main clinical treatment method of gastric cancer. Multidrug resistance
(MDR) has become a common phenomenon with the development of tumors, which …

[HTML][HTML] Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines

S Chai, KKW To, G Lin - Chinese medicine, 2010 - Springer
Multi-drug resistance (MDR) of cancer cells severely limits therapeutic outcomes. A
proposed mechanism for MDR involves the efflux of anti-cancer drugs from cancer cells …

[HTML][HTML] Overcoming Cancer Multi-drug Resistance (MDR): Reasons, mechanisms, nanotherapeutic solutions, and challenges

C Duan, M Yu, J Xu, BY Li, Y Zhao… - Biomedicine & …, 2023 - Elsevier
Multi-drug resistance (MDR) in cancer cells, either intrinsic or acquired through various
mechanisms, significantly hinders the therapeutic efficacy of drugs. Typically, the reduced …

[HTML][HTML] Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancers

L Zhang, B Ye, Z Chen, ZS Chen - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Chemotherapy is one of the important methods to treat cancer, and the emergence of
multidrug resistance (MDR) is one major cause for the failure of cancer chemotherapy …

Compounds from Chinese herbal medicines as reversal agents for P-glycoprotein-mediated multidrug resistance in tumours

C Li, BQ Sun, XD Gai - Clinical and Translational Oncology, 2014 - Springer
Multidrug resistance (MDR) is a major obstacle to successful cancer chemotherapy. One of
the main underlying mechanisms of this resistance is the over-expression of P-glycoprotein …

Research progress of traditional Chinese medicine monomers in reversing multidrug resistance of breast cancer

S Wang, S Yang, X Yang, D Deng, J Li… - The American Journal of …, 2023 - World Scientific
Breast cancer is a malignant disease with an increasing incidence. Chemotherapy is still an
important means for breast cancer treatment, but multidrug resistance (MDR) greatly limits its …

Cancer treatment by using traditional Chinese medicine: probing active compounds in anti-multidrug resistance during drug therapy

JS Lou, P Yao, KWK Tsim - Current Medicinal Chemistry, 2018 - ingentaconnect.com
The main challenge of cancer treatment is multidrug resistance during chemotherapy.
Cancer cell can evade cell death during every round of orthodox chemotherapy drugs …