Humans are exposed to a diverse mixture of chemical and non-chemical exposures across
their lifetimes. Well-designed epidemiology studies as well as sophisticated exposure …

Quantifying the impact of exposure to environmental chemical mixtures is important for
identifying risk factors for diseases and developing more targeted public health …

Traditionally, toxicological studies and human health risk assessments have focused
primarily on single chemicals. However, people are exposed to a myriad of chemical and …

Humans are exposed to a large number of environmental chemicals: Some of these may be
toxic, and many others have unknown or poorly characterized health effects. There is …

All people are exposed to complex and dynamic mixtures of chemicals and nonchemical
stressors throughout their lives. Understanding how these combined exposures impact …

Abstract Purpose of Review The purpose of this review is to outline the main questions in
environmental mixtures research and provide a non-technical explanation of novel or …

Background: The analysis of health effects of exposure to mixtures is a critically important
issue in human epidemiology, and increasing effort is being devoted to developing methods …

Abstract Purpose of This Review This review provides a summary of statistical approaches
that researchers can use to study environmental exposure mixtures. Two primary …

Background: Epidemiological studies are increasingly going beyond the evaluation of health
effects of individual chemicals to consider chemical mixtures. To our knowledge, the …

Differential exposure to mixtures of environmental agents, including biological, chemical,
physical, and psychosocial stressors, can contribute to increased vulnerability of human …