Diagnosis and management of eosinophilic asthma: a US perspective
HH Walford, TA Doherty - Journal of asthma and allergy, 2014 - Taylor & Francis
Eosinophilic asthma is now recognized as an important subphenotype of asthma based on
the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be …
the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be …
Improving the diagnosis of eosinophilic asthma
H Coumou, EH Bel - Expert review of respiratory medicine, 2016 - Taylor & Francis
Introduction: Diagnosing eosinophilic asthma is important, because uncontrolled
eosinophilic airway inflammation is associated with reduced response to glucocorticoids …
eosinophilic airway inflammation is associated with reduced response to glucocorticoids …
[HTML][HTML] Eosinophilic asthma, phenotypes-endotypes and current biomarkers of choice
K Porpodis, I Tsiouprou, A Apostolopoulos… - Journal of Personalized …, 2022 - mdpi.com
Asthma phenotyping and endotyping are constantly evolving. Currently, several biologic
agents have been developed towards a personalized approach to asthma management …
agents have been developed towards a personalized approach to asthma management …
[HTML][HTML] Eosinophilic inflammation: An appealing target for pharmacologic treatments in severe asthma
A Vatrella, A Maglio, C Pelaia, L Ciampo, G Pelaia… - Biomedicines, 2022 - mdpi.com
Severe asthma is characterized by different endotypes driven by complex pathologic
mechanisms. In most patients with both allergic and non-allergic asthma, predominant …
mechanisms. In most patients with both allergic and non-allergic asthma, predominant …
[HTML][HTML] Severe eosinophilic asthma
A Bakakos, S Loukides, P Bakakos - Journal of clinical medicine, 2019 - mdpi.com
Asthma is a heterogeneous disease with varying severity. Severe asthma is a subject of
constant research because it greatly affects patients' quality of life, and patients with severe …
constant research because it greatly affects patients' quality of life, and patients with severe …
[HTML][HTML] Eosinophilic airway diseases: from pathophysiological mechanisms to clinical practice
M Mormile, I Mormile, S Fuschillo, FW Rossi… - International Journal of …, 2023 - mdpi.com
Eosinophils play a key role in airway inflammation in many diseases, such as allergic and
non-allergic asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive …
non-allergic asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive …
[HTML][HTML] Eosinophilic bioactivities in severe asthma
TF Carr, S Berdnikovs, HU Simon, BS Bochner… - World Allergy …, 2016 - Springer
Asthma is clearly related to airway or blood eosinophilia, and asthmatics with significant
eosinophilia are at higher risk for more severe disease. Eosinophils actively contribute to …
eosinophilia are at higher risk for more severe disease. Eosinophils actively contribute to …
[HTML][HTML] Eosinophilic and noneosinophilic asthma
The term “eosinophilic” asthma (EA) generally refers to the clinical inflammatory phenotype
of asthma wherein a significant number of sputum, airway, and/or blood eosinophils are …
of asthma wherein a significant number of sputum, airway, and/or blood eosinophils are …
Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease
L George, CE Brightling - Therapeutic advances in chronic …, 2016 - journals.sagepub.com
The chronic lung diseases, asthma and chronic obstructive pulmonary disease (COPD), are
common affecting over 500 million people worldwide and causing substantial morbidity and …
common affecting over 500 million people worldwide and causing substantial morbidity and …
Eosinophil diversity in asthma
G Van Hulst, HM Batugedara, J Jorssen, R Louis… - Biochemical …, 2020 - Elsevier
Eosinophils are a type of granulated innate immune cells that have long been implicated in
a specific type of asthma, referred to as eosinophilic asthma. Several immunotherapeutics …
a specific type of asthma, referred to as eosinophilic asthma. Several immunotherapeutics …