Exploring the pivotal immunomodulatory and anti‐inflammatory potentials of glycyrrhizic and glycyrrhetinic acids

SA Richard - Mediators of Inflammation, 2021 - Wiley Online Library
Licorice extract is a Chinese herbal medication most often used as a demulcent or elixir. The
extract usually consists of many components but the key ingredients are glycyrrhizic (GL) …

Glycyrrhizic acid suppresses Cox-2-mediated anti-inflammatory responses during Leishmania donovani infection

S Bhattacharjee, A Bhattacharjee… - Journal of …, 2012 - academic.oup.com
Objectives The aim of the present study was to characterize glycyrrhizic acid (GA) and
assess its immunomodulatory potential in a model of experimental visceral leishmaniasis …

Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights

R Jain, MA Hussein, S Pierce, C Martens… - Pharmacological …, 2022 - Elsevier
Licorice (Glycyrrhiza glabra) is a well-known natural herb used to treat different ailments
since ancient times. Glycyrrhizin (GL), which is the primary triterpenoid compound of licorice …

Therapeutic effects of glycyrrhizic acid

LJ Ming, ACY Yin - Natural product communications, 2013 - journals.sagepub.com
Glycyrrhizic acid (GA), belonging to a class of triterpenes, is a conjugate of two molecules,
namely glucuronic acid and glycyrrhetinic acid. It is naturally extracted from the roots of …

Advances in pharmacological activities and mechanisms of glycyrrhizic acid

K Chen, R Yang, FQ Shen… - Current medicinal …, 2020 - ingentaconnect.com
Licorice (Glycyrrhiza glabra L.) is widely regarded as an important medicinal plant and has
been used for centuries in traditional medicine because of its therapeutic properties. Studies …

Glycyrrhizic acid and 18β-glycyrrhetinic acid inhibit inflammation via PI3K/Akt/GSK3β signaling and glucocorticoid receptor activation

TC Kao, MH Shyu, GC Yen - Journal of agricultural and food …, 2010 - ACS Publications
Many lung-related diseases, such as asthma and chronic obstructive pulmonary disease,
are initiated by airway inflammation, and several studies indicate that glycyrrhizic acid (GA) …

Glycyrrhizic acid in the treatment of liver diseases: literature review

J Li, H Cao, P Liu, G Cheng… - BioMed research …, 2014 - Wiley Online Library
Glycyrrhizic acid (GA) is a triterpene glycoside found in the roots of licorice plants
(Glycyrrhiza glabra). GA is the most important active ingredient in the licorice root, and …

[HTML][HTML] Anti-inflammatory activities of licorice extract and its active compounds, glycyrrhizic acid, liquiritin and liquiritigenin, in BV2 cells and mice liver

JY Yu, JY Ha, KM Kim, YS Jung, JC Jung, S Oh - Molecules, 2015 - mdpi.com
This study provides the scientific basis for the anti-inflammatory effects of licorice extract in at-
BHP (tert-butyl hydrogen peroxide)-induced liver damage model and the effects of its …

[HTML][HTML] Revisiting liquorice (Glycyrrhiza glabra L.) as anti-inflammatory, antivirals and immunomodulators: Potential pharmacological applications with mechanistic …

D Bisht, M Rashid, RKK Arya, D Kumar… - Phytomedicine Plus, 2022 - Elsevier
Abstract Background Glycyrrhiza glabra L.(G. glabra) commonly known as liquorice is one of
the highly exploited and utilized medicinal plant of the world. Since ancient times liquorice is …

Dual inhibitory effect of Glycyrrhiza glabra (GutGard™) on COX and LOX products

CV Chandrasekaran, HB Deepak, P Thiyagarajan… - Phytomedicine, 2011 - Elsevier
Glycyrrhiza glabra and its phytoconstituents have been known to possess widespread
pharmacological properties as an anti-inflammatory, anti-viral, antitumour and …