Background: This study aimed to develop a novel drug formulation using
polybutylcyanoacrylate (PBCA) nanoparticles to deliver cisplatin, a commonly used …

Breast cancer is the most common cancer and the second cause of cancer‐related death in
women worldwide. Chemotherapy of disease is impeded by subsequent relapse and …

Nano-drug delivery holds great potential to enhance the efficacy of carboplatin. This study
focused on cytotoxicity, in vitro drug release and characterization of poly (butyl …

This study aims to improve the cytotoxicity and potency of cisplatin-loaded
polybutylcyanoacrylate (PBCA) nanoparticles (NPs) for the treatment of lung cancer through …

One of the main challenges of treatment of ovarian cancer is initial response to treatment
and then acquisition of resistance to Cisplatin. Nanotechnology-based approaches are …

The use of doxorubicin (DOX), one of the most effective antitumor molecules in the treatment
of metastatic breast cancer, is limited by its low tumor selectivity and its severe side effects …

Glioblastoma is known as one of the most aggressive human cancers. To gain access of the
brain, therapeutic agents must overcome blood–brain barrier (BBB). In this study, Cisplatin …

This study aimed to evaluate the therapeutic efficacy of the cisplatin encapsulated into
polybutylcyanoacrylate (PBCA) nanoparticles for the treatment of kidney cancer. The …

Objective: Drug loading into nanocarriers is used to facilitate drug delivery to target cells and
organs. We have previously reported a change in cellular localization of epirubicin after …

Tumor eradication has many challenges due to the difficulty of selectively delivering
anticancer drugs to malignant cells avoiding contact with healthy tissues/organs. The …