Acute myeloid leukaemia

NJ Short, ME Rytting, JE Cortes - The Lancet, 2018 - thelancet.com
For several decades, few substantial therapeutic advances have been made for patients
with acute myeloid leukaemia. However, since 2017 unprecedented growth has been seen …

Acute myeloid leukaemia

CD DiNardo, HP Erba, SD Freeman, AH Wei - The Lancet, 2023 - thelancet.com
Progress in acute myeloid leukaemia treatment is occurring at an unprecedented pace. The
past decade has witnessed an increasingly improved scientific understanding of the …

Harnessing the benefits of available targeted therapies in acute myeloid leukaemia

H Kantarjian, NJ Short, C DiNardo, EM Stein… - The Lancet …, 2021 - thelancet.com
Research has resulted in regulatory approval of nine agents for acute myeloid leukaemia
indications by the US Food and Drug Administration since 2017: the Bcl-2 inhibitor …

Acute myeloid leukemia: 2023 update on diagnosis, risk‐stratification, and management

S Shimony, M Stahl, RM Stone - American Journal of …, 2023 - Wiley Online Library
Disease overview Acute myeloid leukemia (AML) is a frequently fatal bone marrow stem cell
cancer characterized by unbridled proliferation of malignant marrow stem cells with …

[HTML][HTML] Acute myeloid leukemia: a comprehensive review and 2016 update

I De Kouchkovsky, M Abdul-Hay - Blood cancer journal, 2016 - nature.com
Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with an
incidence of over 20 000 cases per year in the United States alone. Large chromosomal …

[HTML][HTML] Recently approved therapies in acute myeloid leukemia: a complex treatment landscape

C Talati, K Sweet - Leukemia research, 2018 - Elsevier
Acute myeloid leukemia (AML) is a heterogeneous disease. Until recently, treatment for
patients with AML was limited to induction chemotherapy with cytarabine and anthracycline …

Acute myeloid leukemia: from mutation profiling to treatment decisions

C DiNardo, C Lachowiez - Current hematologic malignancy reports, 2019 - Springer
Abstract Purpose of Review Awareness of the molecular landscape of AML has improved
AML care over the last 5 years. This review summarizes updates regarding the diagnostic …

Updates on targeted therapies for acute myeloid leukaemia

S Kayser, MJ Levis - British journal of haematology, 2022 - Wiley Online Library
In the past few years research in the underlying pathogenic mechanisms of acute myeloid
leukaemia (AML) has led to remarkable advances in our understanding of the disease …

Acute myeloid leukemia: 2019 update on risk‐stratification and management

EH Estey - American journal of hematology, 2018 - Wiley Online Library
Outcome in patients with acute myeloid leukemia (AML) ranges from death within a few days
of beginning treatment (treatment related mortality, TRM) to likely cure. The major reason …

[HTML][HTML] Recent drug approvals for acute myeloid leukemia

C Lai, K Doucette, K Norsworthy - Journal of hematology & oncology, 2019 - Springer
Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with an
incidence that increases with age, and a generally poor prognosis. The disease is clinically …