Mesoporous silica nanoparticles for efficient rivastigmine hydrogen tartrate delivery into SY5Y cells
M Karimzadeh, L Rashidi, F Ganji - Drug development and …, 2017 - Taylor & Francis
Rivastigmine hydrogen tartrate (RT) is a molecule with both hydrophilic and hydrophobic
properties used for the treatment of the Alzheimer's disease. In this work, the larger pore size …
properties used for the treatment of the Alzheimer's disease. In this work, the larger pore size …
Polysorbate-coated mesoporous silica nanoparticles as an efficient carrier for improved rivastigmine brain delivery
Targeted delivery of neurological therapeutic to the brain has been attracting more and more
attention to the treatment of central nervous system (CNS) diseases. Nonetheless, the main …
attention to the treatment of central nervous system (CNS) diseases. Nonetheless, the main …
MCM-41 nanoparticles for brain delivery: better choline-esterase and amyloid formation inhibition with improved kinetics
The present study was aimed at delivering a low bioavailability drug, rivastigmine hydrogen
tartrate (RTG), to the brain through its encapsulation in mesoporous silica nanoparticles …
tartrate (RTG), to the brain through its encapsulation in mesoporous silica nanoparticles …
Development and evaluation of rivastigmine loaded chitosan nanoparticles for brain targeting
The rivastigmine (RHT) loaded chitosan nanoparticles (CS-RHT NPs) were prepared by
ionic gelation method to improve the bioavailability and enhance the uptake of RHT to the …
ionic gelation method to improve the bioavailability and enhance the uptake of RHT to the …
Surface functionalized mesoporous silica nanoparticles as an effective carrier for epirubicin delivery to cancer cells
Recent studies with inorganic nanoparticles modified with functional groups have
demonstrated improvement in drug delivery into cancer cells. In the present study, we …
demonstrated improvement in drug delivery into cancer cells. In the present study, we …
Evaluation of biomimetically synthesized mesoporous silica nanoparticles as drug carriers: structure, wettability, degradation, biocompatibility and brain distribution
H Li, X Wu, B Yang, J Li, L Xu, H Liu, S Li, J Xu… - Materials Science and …, 2019 - Elsevier
Herein, three kinds of mesoporous silica nanoparticles (BMSs) were biomimetically
synthesized by using heterocyclic amino acid derivatives as template and their the basic …
synthesized by using heterocyclic amino acid derivatives as template and their the basic …
Development of MCM-41 mesoporous silica nanoparticles as a platform for pramipexole delivery
B Tzankov, V Tzankova, D Aluani, Y Yordanov… - Journal of Drug Delivery …, 2019 - Elsevier
Herein, we present development of new pH-responsive drug delivery systems for D3-
dopamine receptor agonist pramipexole, based on its encapsulation in MCM-41 …
dopamine receptor agonist pramipexole, based on its encapsulation in MCM-41 …
Potential therapeutic effect of nanobased formulation of rivastigmine on rat model of Alzheimer's disease
MF Ismail, AN ElMeshad… - International journal of …, 2013 - Taylor & Francis
Background To sustain the effect of rivastigmine, a hydrophilic cholinesterase inhibitor,
nanobased formulations were prepared. The efficacy of the prepared rivastigmine liposomes …
nanobased formulations were prepared. The efficacy of the prepared rivastigmine liposomes …
Functionalized silica nanoparticles as a carrier for Betamethasone Sodium Phosphate: Drug release study and statistical optimization of drug loading by response …
Mesoporous silica nanoparticles with a hexagonal structure (SBA-15) were synthesized and
modified with (3-aminopropyl) triethoxysilane (APTES), and their performance as a carrier …
modified with (3-aminopropyl) triethoxysilane (APTES), and their performance as a carrier …
Development and in vitro safety evaluation of pramipexole-loaded hollow mesoporous silica (HMS) particles
In this study, spherical hollow mesoporous silica (HMS) particles with average size of 550
nm were loaded with dopamine-receptor agonist pramipexole, as a model drug. High drug …
nm were loaded with dopamine-receptor agonist pramipexole, as a model drug. High drug …
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