Effector proteins secreted by the type 3 secretion system (T3SS) of pathogenic bacteria have
been shown to precisely modulate important signaling cascades of the host for the benefit of …

The NF-κB signaling pathway is central to the innate and adaptive immune responses. Upon
their detection of pathogen-associated molecular patterns, Toll-like receptors on the cell …

Many bacterial pathogens utilize a type III secretion system (T3SS) to inject virulence effector
proteins into host cells during infection. Previously, we found that enteropathogenic …

Many pathogenic bacteria utilize the type III secretion system (T3SS) to translocate effector
proteins directly into host cells, facilitating colonization. In enterohemmorhagic Escherichia …

Enteropathogenic Escherichia coli (EPEC) is a gastrointestinal pathogen that utilizes a type
III secretion system (T3SS) to inject an array of virulence effector proteins into host …

Enteropathogenic Escherichia coli (EPEC), a common cause of infant diarrhea, is
associated with high risk of mortality in developing countries. The primary niche of infecting …

Attaching/Effacing (A/E) pathogens including enteropathogenic Escherichia coli (EPEC),
enterohemorrhagic E. coli (EHEC) and the rodent equivalent Citrobacter rodentium are …

Upon infection of epithelial cells, enteropathogenic E scherichia coli suppresses host cell
inflammatory signalling in a type III secretion system (T3SS) dependent manner. Two key …

The enteric pathogens enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E.
coli employ a type 3 secretion system (T3SS) to manipulate the host inflammatory response …

To successfully infect host cells and evade the host immune response, a type III secretion
system (T3SS) is commonly used by enteric bacterial pathogens such as enteropathogenic …