Proteomics: a pragmatic perspective

P Mallick, B Kuster - Nature biotechnology, 2010 - nature.com
The evolution of mass spectrometry–based proteomic technologies has advanced our
understanding of the complex and dynamic nature of proteomes while concurrently …

Proteomics: translating genomics into products?

A Dove - Nature biotechnology, 1999 - nature.com
By cataloging the entire protein content of a cell, proteomics should not only provide insight
into the molecular basis of life, but also accelerate the identification of molecular targets for …

Proteomics technologies and challenges

WCS Cho - Genomics, Proteomics and Bioinformatics, 2007 - academic.oup.com
Proteomics is the study of proteins and their interactions in a cell. With the completion of the
Human Genome Project, the emphasis is shifting to the protein compliment of the human …

Quantitative proteomics: challenges and opportunities in basic and applied research

OT Schubert, HL Röst, BC Collins, G Rosenberger… - Nature protocols, 2017 - nature.com
In this Perspective, we discuss developments in mass-spectrometry-based proteomic
technology over the past decade from the viewpoint of our laboratory. We also reflect on …

Proteomics retrenches

P Mitchell - Nature biotechnology, 2010 - nature.com
Proteomics retrenches | Nature Biotechnology Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Proteomics meets the scientific method

P Picotti, B Bodenmiller, R Aebersold - Nature methods, 2013 - nature.com
Proteomics meets the scientific method | Nature Methods Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

The need for a public proteomics repository

JT Prince, MW Carlson, R Wang, P Lu… - Nature …, 2004 - nature.com
COMMENTARY a recent large scale analysis of the yeast proteome19), underlining the
need for improved algorithms for interpreting these raw data, and for recognizing when …

The biological impact of mass-spectrometry-based proteomics

BF Cravatt, GM Simon, JR Yates Iii - Nature, 2007 - nature.com
In the past decade, there have been remarkable advances in proteomic technologies. Mass
spectrometry has emerged as the preferred method for in-depth characterization of the …

Molecular biologist's guide to proteomics

PR Graves, TAJ Haystead - Microbiology and molecular biology …, 2002 - Am Soc Microbiol
The emergence of proteomics, the large-scale analysis of proteins, has been inspired by the
realization that the final product of a gene is inherently more complex and closer to function …

Proteomics in non-model organisms: a new analytical frontier

M Heck, BA Neely - Journal of proteome research, 2020 - ACS Publications
For the last century we have relied on model organisms to help understand fundamental
biological processes. Now, with advancements in genome sequencing, assembly, and …