Background: Maternal obesity and diabetes are both associated with increased risk of
congenital central nervous system (CNS) malformations in the offspring and may share a …

Objective. Several studies have shown an increased risk for neural tube defects associated
with prepregnancy maternal obesity. Because few recent studies have examined the relation …

Objectives: To examine the association between maternal prepregnancy weight and child
neurodevelopment, and the effect of gestational weight gain. Methods: Using the US …

This study was designed to evaluate the effects of maternal obesity and diabetes mellitus on
the risk of nonchromosomal congenital defects. We used data from 22,951 pregnant women …

To determine whether the risk of having an infant with anencephaly or spina bifida is greater
among obese women than among average-weight women, we compared 307 Atlanta-area …

Maternal obesity in pregnancy is associated with a number of adverse outcomes for mother
and her offspring both perinatally and later in life. This includes recent evidence that …

Although both maternal obesity and diabetes mellitus increase the risk for neural tube
defects, it is unknown whether they are independent risk factors or manifestations of an …

OBJECTIVE: Our purpose was to determine whether obese women and underweight
women have an increased risk of birth defects in their offspring. STUDY DESIGN: A …

Previous studies have observed an increased risk of approximately twofold or more for
neural tube defects (NTD) associated with maternal obesity before pregnancy based on a …

Objective To describe the relation between maternal obesity, overweight and underweight
status, and 16 categories of structural birth defects. Design An ongoing multisite, case …