Heterogeneity of cancer means many tumorigenic genes are only aberrantly expressed in a
subset of patients and thus follow a bimodal distribution, having two modes of expression …

MicroRNAs (miRNAs) are small endogenous regulatory molecules that modulate gene
expression post-transcriptionally. Although differential expression of miRNAs have been …

MicroRNAs (miRNAs) have emerged as key genetic regulators of a wide variety of biological
processes, including growth, proliferation, and survival. Recent advances have led to the …

Biomarkers predictive of drug-specific outcomes are important tools for personalized
medicine. In this study, we present an integrative analysis to identify miRNAs that are …

Dysregulation of microRNAs (miRNAs) is extensively associated with cancer development
and progression. miRNAs have been shown to be biomarkers for predicting tumor formation …

Recently, both 5p and 3p miRNA strands are being recognized as functional instead of only
one, leaving many miRNA strands uninvestigated. To determine whether both miRNA …

MicroRNAs (miRNAs), which play critical roles in gene regulatory networks, have emerged
as promising diagnostic and prognostic biomarkers for human cancer. In particular …

Background microRNAs (miRNAs) regulate target genes at the post-transcriptional level and
play important roles in cancer pathogenesis and development. Variation amongst …

Background Clinical statement alone is not enough to predict the progression of disease.
Instead, the gene expression profiles have been widely used to forecast clinical outcomes …

Epitranscriptomic studies of miRNAs have added a new layer of complexity to the cancer
field. Although there is fast-growing interest in adenosine-to-inosine (A-to-I) miRNA editing …