Reduced-intensity conditioning followed by allogeneic hematopoietic cell transplantation in myeloid diseases

U Platzbecker, G Ehninger, N Schmitz… - Annals of …, 2003 - Springer
Within the past years, reduced or modified doses of chemotherapy or radiotherapy have
been widely studied for conditioning before allogeneic hematopoietic cell transplantation in …

[HTML][HTML] Myeloablative versus reduced-intensity conditioning in patients with myeloid malignancies: a propensity score-matched analysis

H Sibai, U Falcone, U Deotare, FV Michelis… - Biology of Blood and …, 2016 - Elsevier
Reduced-intensity conditioning (RIC) has been shown to have similar overall survival (OS)
but higher relapse rates compared with myeloablative (MAC) regimens in patients with …

[HTML][HTML] Reduced-intensity conditioning with fludarabine, melphalan, and total body irradiation for allogeneic hematopoietic cell transplantation: the effect of increasing …

GL Chen, T Hahn, GE Wilding, A Groman… - Biology of Blood and …, 2019 - Elsevier
Disease relapse and toxicity are the shortcomings of reduced-intensity conditioning (RIC) for
allogeneic hematopoietic cell transplantation (alloHCT). We hypothesized that adding total …

Reduced intensity conditioning for acute myeloid leukemia using melphalan-vs busulfan-based regimens: a CIBMTR report

Z Zhou, R Nath, J Cerny, HL Wang, MJ Zhang… - Blood …, 2020 - ashpublications.org
There is a lack of large comparative study on the outcomes of reduced intensity conditioning
(RIC) in acute myeloid leukemia (AML) transplantation using fludarabine/busulfan (FB) and …

[HTML][HTML] Allogeneic hematopoietic stem cell transplantation for the treatment of high-risk acute myelogenous leukemia and myelodysplastic syndrome using reduced …

B Oran, S Giralt, R Saliba, C Hosing, U Popat… - Biology of Blood and …, 2007 - Elsevier
Reduced-intensity conditioning has extended the use of allogeneic hematopoietic stem cell
transplantation (HSCT) to patients otherwise not eligible for this treatment due to older age …

[HTML][HTML] Myeloablative versus reduced-intensity conditioning for hematopoietic cell transplantation in acute myelogenous leukemia and myelodysplastic syndromes …

BL Scott, MC Pasquini, M Fei, R Fraser, J Wu… - … and cellular therapy, 2021 - Elsevier
Several prospective randomized trials comparing conditioning intensity before allogeneic
hematopoietic cell transplantation (HCT) have been performed, with conflicting results …

Reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation in myelodysplastic syndromes and acute myelogenous leukemia

D Valcárcel, R Martino - Current Opinion in Oncology, 2007 - journals.lww.com
Allogeneic stem cell transplantation with reduced intensity conditioning allows many
patients considered ineligible for standard myeloablative conditioning to benefit from this …

Reduced-Intensity Conditioning in Allogeneic StemCell Transplantation for Hematological Malignancies: A Historical Perspective

B Cremer, BM Sandmaier, W Bethge, T Lange… - Oncology Research …, 2011 - karger.com
Allogeneic hematopoietic stem cell transplantation represents a curative treatment approach
for a large range of hematologic malignancies. Traditionally, high-dose radiochemotherapy …

Reduced intensity vs. myeloablative conditioning with fludarabine and PK-guided busulfan in allogeneic stem cell transplantation for patients with AML/MDS

G Alatrash, KM Kidwell, PF Thall, A Di Stasi… - Bone marrow …, 2019 - nature.com
Conditioning regimens contribute significantly to outcomes following allogeneic stem cell
transplantation (allo-SCT). Reduced-intensity conditioning (RIC) regimens provide lower …

Survival benefits from reduced‐intensity conditioning in allogeneic stem cell transplantation for young lower‐risk MDS patients without significant comorbidities

SE Lee, YJ Kim, SA Yahng, BS Cho… - European Journal of …, 2011 - Wiley Online Library
Objective: The aim of this study was to determine the optimum conditioning intensity for
allogeneic stem cell transplantation (SCT) in young (age≤ 50), lower‐risk (INT‐1 by IPSS) …