[HTML][HTML] Is the activity-based anorexia model a reliable method of presenting peripheral clinical features of anorexia nervosa?

K Skowron, M Kurnik-Łucka, M Jurczyk… - Nutrients, 2021 - mdpi.com
Anorexia nervosa (AN) causes the highest number of deaths among all psychiatric
disorders. Reduction in food intake and hyperactivity/increased anxiety observed in AN are …

Establishment of a chronic activity-based anorexia rat model

L Frintrop, S Trinh, J Liesbrock, L Paulukat… - Journal of neuroscience …, 2018 - Elsevier
Background Anorexia nervosa (AN) is often a chronic eating disorder characterised by body
image disturbance and low body weight often associated with starvation-induced …

[HTML][HTML] Activity based anorexia as an animal model for anorexia nervosa–a systematic review

MA Schalla, A Stengel - Frontiers in nutrition, 2019 - frontiersin.org
Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons.
However, the knowledge about its underlying pathophysiology is limited. To address the …

[HTML][HTML] Establishment of a murine chronic anorexia nervosa model

A Staffeld, S Gill, A Zimmermann, N Böge, K Schuster… - Cells, 2023 - mdpi.com
Anorexia nervosa (AN) is associated with hyperactivity, amenorrhea, and brain atrophy. The
underlying pathophysiology is mostly unknown, and new targets for therapeutic …

[HTML][HTML] Activity-based anorexia reduces body weight without inducing a separate food intake microstructure or activity phenotype in female rats—mediation via an …

S Scharner, P Prinz, M Goebel-Stengel… - Frontiers in …, 2016 - frontiersin.org
Anorexia nervosa (AN) is accompanied by severe somatic and psychosocial complications.
However, the underlying pathogenesis is poorly understood, treatment is challenging and …

Fear and food: Anxiety‐like behavior and the susceptibility to weight loss in an activity‐based anorexia rat model

C Schwenzer, C Voelz, V Kogel… - Clinical and …, 2022 - Wiley Online Library
Anorexia nervosa (AN) is a severe psychiatric disorder characterized by energy restriction,
low body weight, a fear of gaining weight, and often excessive physical activity. Anxiety …

In pursuit of biomarkers for predicting susceptibility to activity‐based anorexia in adolescent female rats

LK Milton, T Patton, M O'Keeffe… - … Journal of Eating …, 2022 - Wiley Online Library
Objective Identifying risk factors that contribute to the development of anorexia nervosa (AN)
is critical for the implementation of early intervention strategies. Anxiety, obsessive …

[HTML][HTML] Animal models for anorexia nervosa—a systematic review

S Scharner, A Stengel - Frontiers in Human Neuroscience, 2021 - frontiersin.org
Anorexia nervosa is an eating disorder characterized by intense fear of gaining weight and a
distorted body image which usually leads to low caloric intake and hyperactivity. The …

Influence of early maternal separation on susceptibility to the activity-based anorexia model in male and female Sprague Dawley rats

GSK Morgan, Y Mata, B Carrillo, RPS de Puga… - Neuroscience …, 2022 - Elsevier
A principal animal paradigm employed in Anorexia Nervosa (AN) study is the activity-based
anorexia (ABA) model. The model's efficacy in recapitulating the core features of AN in …

[HTML][HTML] Olanzapine, but not fluoxetine, treatment increases survival in activity-based anorexia in mice

SJ Klenotich, MP Seiglie, MS McMurray… - …, 2012 - nature.com
Anorexia nervosa (AN) is an eating disorder characterized by extreme hypophagia,
hyperactivity, and fear of weight gain. No approved pharmacological treatments exist for AN …