Inflammation mediated epileptogenesis as possible mechanism underlying ischemic post-stroke epilepsy

AR Tröscher, J Gruber, JN Wagner, V Böhm… - Frontiers in aging …, 2021 - frontiersin.org
Post-stroke Epilepsy (PSE) is one of the most common forms of acquired epilepsy,
especially in the elderly population. As people get increasingly older, the number of stroke …

Neuroinflammatory mediators in acquired epilepsy: an update

Y Chen, MM Nagib, N Yasmen, MN Sluter… - Inflammation …, 2023 - Springer
Epilepsy is a group of chronic neurological disorders that have diverse etiologies but are
commonly characterized by spontaneous seizures and behavioral comorbidities. Although …

Neuroinflammation in epileptogenesis: from pathophysiology to therapeutic strategies

W Li, J Wu, Y Zeng, W Zheng - Frontiers in Immunology, 2023 - frontiersin.org
Epilepsy is a group of enduring neurological disorder characterized by spontaneous and
recurrent seizures with heterogeneous etiology, clinical expression, severity, and prognosis …

Insights into inflammation and epilepsy from the basic and clinical sciences

G Silveira, ACP De Oliveira, AL Teixeira - Journal of Clinical Neuroscience, 2012 - Elsevier
Inflammatory mediators are overexpressed in brain tissue after induction of seizures in
animal models, and several studies demonstrate their involvement in neuronal …

Behavioral comorbidities of epilepsy and neuroinflammation: Evidence from experimental and clinical studies

EM Suleymanova - Epilepsy & Behavior, 2021 - Elsevier
Currently, a significant amount of data is accumulated showing that neuroinflammation is
one of the key processes in the development of brain pathology in trauma …

Neuroinflammation in post-traumatic epilepsy: pathophysiology and tractable therapeutic targets

R Sharma, WL Leung, A Zamani, TJ O'brien… - Brain sciences, 2019 - mdpi.com
Epilepsy is a common chronic consequence of traumatic brain injury (TBI), contributing to
increased morbidity and mortality for survivors. As post-traumatic epilepsy (PTE) is drug …

Neuroinflammation: a signature or a cause of epilepsy?

E Pracucci, V Pillai, D Lamers, R Parra… - International journal of …, 2021 - mdpi.com
Epilepsy can be both a primary pathology and a secondary effect of many neurological
conditions. Many papers show that neuroinflammation is a product of epilepsy, and that in …

The role of neuroinflammation in post-traumatic epilepsy

L Sun, W Shan, H Yang, R Liu, J Wu, Q Wang - Frontiers in Neurology, 2021 - frontiersin.org
Post-traumatic epilepsy (PTE) is one of the consequences after traumatic brain injury (TBI),
which increases the morbidity and mortality of survivors. About 20% of patients with TBI will …

Epilepsy and brain inflammation

A Vezzani, E Aronica, A Mazarati, QJ Pittman - Experimental neurology, 2013 - Elsevier
During the last decade, experimental research has demonstrated a prominent role of glial
cells, activated in brain by various injuries, in the mechanisms of seizure precipitation and …

Reactive glia inflammatory signaling pathways and epilepsy

P Sanz, MA Garcia-Gimeno - International journal of molecular sciences, 2020 - mdpi.com
Neuroinflammation and epilepsy are interconnected. Brain inflammation promotes neuronal
hyper-excitability and seizures, and dysregulation in the glia immune-inflammatory function …