Of the many serotonin receptors, the type 3 receptors (5-HT3R) are the only ionotropic ones,
playing a key role in fast synaptic transmission and cognitive and emotional brain function …

5-HT3 receptors are members of the Cys-loop family of ligand-gated ion channels, and, like
most members of this family, there are multiple subunits that can contribute to functional …

Serotonin (5-HT) is a neurotransmitter that plays an important role in neuronal plasticity.
Variations in the levels of 5-HT at the synaptic cleft, expression or dysfunction of 5-HT …

Serotonin receptors of the 5-HT2A subtype are robustly expressed in the cerebral cortex
where they have been implicated in the pathophysiology and therapeutics of mental …

The present study is the first one to demonstrate the expression of 5-HT7 receptor mRNA by
in situ hybridization during postnatal development. No quantitative developmental changes …

5-HT4 receptors mediate several physiological effects of 5-HT, particularly in the central
nervous system (CNS), heart and gut. Recently, several C-terminal splice variants of the …

Serotonin (5-hydroxytryptamine or 5-HT) is an important neurotransmitter regulating a wide
range of physiological and pathological functions via activation of heterogeneously …

Pharmacological and genetic tools targeting the 5-hydroxytryptamine (5-HT) 7 receptor in
preclinical animal models have implicated this receptor in diverse (patho) physiological …

Serotonin (5-hydroxytryptamine, 5-HT), next to being an important neurotransmitter, recently
gained attention as a key-regulator of pre-and postnatal development in the mammalian …

The 5‐HT2C receptor has been implicated in mood and eating disorders. In general, it is
accepted that 5‐HT2C receptor agonists increase anxiety behaviours and induce …