[图书][B] Allergic contact dermatitis: chemical and metabolic mechanisms

C Smith - 2023 - taylorfrancis.com
llergic Contact Dermatitis assesses the potential effects of xenobiotic metabolism and
protein reactivity on toxicity. It reviews current knowledge of percutaneous absorption and …

From xenobiotic chemistry and metabolism to better prediction and risk assessment of skin allergy

CKS Pease - Toxicology, 2003 - Elsevier
Allergic contact dermatitis (ACD) is a condition that can have a serious impact on quality of
life. The manifestation of ACD is dependent upon the primary sensitisation of an individual to …

[图书][B] Allergic contact dermatitis: the molecular basis

RJG Rycroft - 2012 - books.google.com
Allergic Contact Dermatitis presents all up-to-date chemical and physio-chemical concepts
for the study and understanding of allergic contact dermatitis (ACD). The book covers all …

The importance of exposure estimation in the assessment of skin sensitization risk

MK Robinson, GF Gerberick, CA Ryan… - Contact …, 2000 - Wiley Online Library
The development of new ingredients and products for the consumer market requires a
thorough assessment of their potential for skin sensitization and the possible clinical …

Drug skin metabolites and allergic drug reactions

HF Merk - Current opinion in allergy and clinical immunology, 2009 - journals.lww.com
Drug skin metabolites and allergic drug reactions : Current Opinion in Allergy and Clinical
Immunology Drug skin metabolites and allergic drug reactions : Current Opinion in Allergy and …

Molecular aspects in allergic and irritant contact dermatitis

JP Lepoittevin, C Lafforgue - Contact dermatitis, 2020 - Springer
Skin exposure to chemicals, natural or synthetic, may result in adverse reactions ranging
from mild irritation to cutaneous allergy. These inflammatory reactions, subsequent to …

Allergic contact dermatitis

I Kimber, DA Basketter, GF Gerberick… - International …, 2002 - Elsevier
Allergic contact dermatitis (ACD) is a common occupational and environmental health issue.
In common with other forms of allergy the disease progresses in two stages; an initial phase …

Does irritation potency contribute to the skin sensitization potency of contact allergens?

DA Basketter, D Kan-King-Yu, P Dierkes… - Cutaneous and ocular …, 2007 - Taylor & Francis
Chemicals that possess the capacity to cause skin sensitization have long been recognized
to be reactive (electrophilic) or at least the precursor of an electrophile. The chemical …

Factors affecting thresholds in allergic contact dermatitis: safety and regulatory considerations

DA Basketter, P Evans, GF Gerberick… - Contact …, 2002 - Wiley Online Library
Although it is now well understood that thresholds exist for both the induction and the
elicitation of allergic responses, such as those of allergic contact dermatitis, it must also be …

Allergic contact dermatitis elicitation thresholds of potent allergens in humans

E Jerschow, JJ Hostýnek, HI Maibach - Food and chemical toxicology, 2001 - Elsevier
Literature scoured for human allergenicity to individual chemicals yields a limited number of
potent sensitizers, which can be classified in four categories: metals, botanicals, biocides …