Kashin–Beck disease (KBD) is a degenerative osteoarticular disorder, and displays the
significant differences with osteoarthritis (OA) regarding the etiology and molecular changes …

Abstract Background Kashin-Beck disease (KBD) is an endemic osteochondropathy of
unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar …

Objective To determine genome-wide DNA methylation profiles of knee cartilage from
patients with Kashin-Beck disease (KBD) and osteoarthritis (OA). Method Knee cartilage …

Objective Epigenetic modifications of DNA are regarded as a crucial factor for understanding
the molecular basis of complex phenotypes. This study aims to uncover insight into the …

To understand how differentially methylated genes (DMGs) might affect the pathogenesis of
Kashin-Beck disease (KBD). Genome-wide methylation profiling of whole blood from 12 …

Kashin-Beck disease (KBD) is an endemic chronic osteochondropathy. The etiology of KBD
remains unknown. In this study, we conducted an integrative analysis of genome-wide DNA …

Kashin-Beck disease (KBD) is an endemic, degenerative osteoarthropathy that exhibits
some similar characteristics to osteoarthritis (OA) but with different etiologies and …

Kashin–beck disease (KBD) is endemic chronic osteoarthrosis and its pathogenesis is still
unclear. The present study aimed to explore differential gene expression in articular …

The pathological mechanism of Kashin-Beck disease (KBD), an endemic osteoarthritic
disease, remains to be poorly understood. This study was designed to identify signaling …

Kashin–Beck disease (KBD) is a serious osteoarthropathia, mainly characterized by
excessive chondrocyte necrosis and apoptosis. The molecular signaling pathways …