Decellularization of human stromal refractive lenticules for corneal tissue engineering

GHF Yam, NZBM Yusoff, TW Goh, M Setiawan… - Scientific reports, 2016 - nature.com
Small incision lenticule extraction (SMILE) becomes a procedure to correct myopia. The
extracted lenticule can be used for other clinical scenarios. To prepare for allogeneic …

Reshaping and customization of SMILE-derived biological lenticules for intrastromal implantation

IB Damgaard, AK Riau, YC Liu, ML Tey… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: To evaluate the feasibility of excimer laser reshaping of biological lenticules
available after small incision lenticule extraction (SMILE). Methods: Fresh and …

Preservation of corneal stromal lenticule

M Nemcokova, J Dite, YM Klimesova, M Netukova… - Cell and Tissue …, 2022 - Springer
Corneal stromal lenticule is a part of corneal stroma, which can be created by manual
dissection, by femtosecond laser from the donor cornea, but chiefly it is a waste product of a …

Construction of a corneal stromal equivalent with SMILE-derived lenticules and fibrin glue

H Yin, P Qiu, F Wu, W Zhang, W Teng, Z Qin, C Li… - Scientific reports, 2016 - nature.com
The scarcity of corneal tissue to treat deep corneal defects and corneal perforations remains
a challenge. Currently, small incision lenticule extraction (SMILE)-derived lenticules appear …

Human SMILE-derived stromal lenticule scaffold for regenerative therapy: Review and perspectives

M Santra, YC Liu, V Jhanji, GHF Yam - International Journal of Molecular …, 2022 - mdpi.com
A transparent cornea is paramount for vision. Corneal opacity is one of the leading causes of
blindness. Although conventional corneal transplantation has been successful in recovering …

Biological corneal inlay for presbyopia derived from small incision lenticule extraction (SMILE)

YC Liu, EPW Teo, HP Ang, XY Seah, NC Lwin… - Scientific reports, 2018 - nature.com
Corneal inlays are a relatively new treatment option for presbyopia. Using biological inlays,
derived from lenticules extracted from small incision lenticule extraction, may offer …

[HTML][HTML] Applications of SMILE-extracted lenticules in ophthalmology

H Aghamollaei, H Hashemi, M Fallahtafti… - International Journal …, 2024 - ncbi.nlm.nih.gov
AIM To review recent innovations, challenges, and applications of small incision lenticule
extraction (SMILE) extracted lenticule for treating ocular disorders. METHODS A literature …

Corneal lenticule allotransplantation after femtosecond laser small incision lenticule extraction in rabbits

J Zhao, Y Shen, M Tian, L Sun, Y Zhao, X Zhang… - Cornea, 2017 - journals.lww.com
Purpose: To investigate the feasibility of allotransplanting extracted lenticules after
femtosecond laser-assisted small incision lenticule extraction (SMILE) in rabbits and the …

Scaffold‐free tissue engineering of functional corneal stromal tissue

FN Syed‐Picard, Y Du, AJ Hertsenberg… - Journal of tissue …, 2018 - Wiley Online Library
Blinding corneal scarring is predominately treated with allogeneic graft tissue; however,
there is a worldwide shortage of donor tissue leaving millions in need of therapy. Human …

Generation of femtosecond laser‐cut decellularized corneal lenticule using hypotonic trypsin‐EDTA solution for corneal tissue engineering

MI Huh, KP Lee, J Kim, S Yi, BU Park… - Journal of …, 2018 - Wiley Online Library
Purpose. To establish an optimized and standardized protocol for the development of
optimal scaffold for bioengineering corneal substitutes, we used femtosecond laser to …