Poly (A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but
difficulties in globally measuring poly (A)-tail lengths have impeded greater understanding of …

Poly (A) tails are important elements in mRNA translation and stability, although recent
genome-wide studies have concluded that poly (A) tail length is generally not associated …

Global investigation of the 3′ extremity of mRNA (3′-terminome), despite its importance in
gene regulation, has not been feasible due to technical challenges associated with …

Poly (A) tails are critical for mRNA stability and translation. However, recent studies have
challenged this view, showing that poly (A) tail length and translation efficiency are …

Although messenger RNAs are key molecules for understanding life, until now, no method
has existed to determine the full-length sequence of endogenous mRNAs including their …

Eukaryotic mRNAs are subject to multiple types of tailing that critically influence mRNA
stability and translatability. To investigate RNA tails at the genomic scale, we previously …

A fundamental principle in biology is that the program for early development is established
during oogenesis in the form of the maternal transcriptome,. How the maternal transcriptome …

Control of poly (A) tail length can affect translation and stability of eukaryotic mRNAs.
Although well established for individual cases, it was not known to what extent this type of …

Beyond the well-known function of poly (A) tail length in mRNA stability, recent years have
witnessed an explosion of information about how changes in tail length and the selection of …

Poly (A) tails have long been known as stable 3′ modifications of eukaryotic mRNAs,
added during nuclear pre‐mRNA processing. It is now appreciated that this modification is …