Every year, more Cu (II) complexes are proven to be biologically active species, but very few
are developed as drugs or entered in clinical trials. This is due to their poor water solubility …

Here, the synthesis and characterization of three improved nanosystems is presented based
on amino functionalized hyperbranched polyglycerol (hPG; Mw= 16.8 kDa) as potential …

Historically, many useful drugs have been developed from natural sources and their
mechanisms of action deeply investigated for therapeutic applications. Recently, the …

Colorectal carcinoma is a complex malignancy and current therapies are hampered by
systemic toxicity and tumor resistance to treatment. In the field of cancer therapy, copper …

Aim: To develop an optimized approach for encapsulating a 2-alkylthioimidazolone-based
copper coordination compound within liposomes, which could offer treatment of cancer and …

The aim of this study was to construct a nanostructured lipid system as a strategy to improve
the in vitro antibacterial activity of copper (II) complexes. New compounds with the general …

Copper is an essential trace element found ubiquitously in humans [1, 2], plants [3–5],
vertebrates and invertebrates [6], and is present in different active sites at innumerous …

Three new copper (II) complexes formulated as [Cu (L)(X)], where X= H 2 O or Cl and H 2 L
is a Schiff base (H 2 L 1, 2) or its reduced version (H 3 L 3 Cl) derived from pyridoxal, are …

Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …

Copper is present in different concentrations and chemical forms throughout the earth crust,
surface and deep water and even, in trace amounts, in the atmosphere itself. Copper is one …