GH exerts a diverse array of physiological actions that include prominent roles in growth and
metabolism, with a major contribution via stimulating IGF-1 synthesis. GH achieves its effects …

Growth hormone (GH) is a major regulatory factor for overall body growth as evidenced by
the height extremes in people with abnormal circulating GH levels or GH receptor (GHR) …

In mammals, the neuroendocrine system, which includes the communication between the
hypothalamus and the pituitary, plays a major role in controlling body growth and cellular …

Growth hormone (GH) plays a pivotal role in many physiological processes in humans, and
in other mammalian and non-mammalian vertebrate species, through actions on somatic …

Growth hormone (GH), a master regulator of somatic growth, also regulates carbohydrate
and lipid metabolism via complex interactions with insulin and insulin-like growth factor-1 …

The understanding of the mechanisms of growth hormone (GH) action has seen great
accomplishments over the last two decades. These achievements include the cloning of a …

Epigenetic mechanisms play an important role in the regulation of the Growth Hormone-
Insulin-like Growth Factor 1 (GH-IGF1) axis and in processes for controlling long bone …

Obesity has become one of the most common medical problems in developed countries,
and this disorder is associated with high incidences of hypertension, dyslipidaemia …

The growth hormone receptor (GHR) is a critical regulator of postnatal growth and
metabolism. However, the GHR signaling domains and pathways that regulate these …

Longitudinal growth in humans follows a unique pattern that is character-ized by rapid fetal
growth, deceleration immediately after birth, a prolonged childhood growth phase, an …