Glucocorticoids are widely used to suppress inflammation or the immune system. High
doses and long-term use of glucocorticoids lead to an important and common iatrogenic …

Glucocorticoid-induced osteoporosis occurs in two phases: a rapid, early phase in which
bone mineral density is reduced, possibly as a result of excessive bone resorption, and a …

Glucocorticoid-induced osteoporosis (GIO) is the most common form of secondary
osteoporosis. Fractures, which are often asymptomatic, may occur in as many as 30–50% of …

Background: Chronic diseases of many organ systems require long-term (≥ 1 year)
treatment with glucocorticoids. Owing to the catabolic activity of glucocorticoid therapy …

Glucocorticoids are widely used to treat several diseases; however, one of their major
consequences is a deleterious effect on bone that may lead to glucocorticoid-induced …

Glucocorticoid excess carries the risk of inducing secondary osteoporosis. In endogenous
Cushing's syndrome, osteoporosis may be the presenting symptom of the underlying …

Glucocorticoid-induced osteoporosis is the most common secondary cause of osteoporosis
and the resulting fractures cause significant morbidity. Following initiation of oral …

Abstract Purpose of this Review The goal of the review is to provide an updated
understanding of the pathophysiology of glucocorticoid-induced osteoporosis and treatment …

Therapeutic use of glucocorticoids can lead to many well-known adverse events [1]. Of all
potential serious side effects, glucocorticoid-induced osteoporosis (GIOP) is one of the most …

Glucocorticoid-induced osteoporosis is a common condition that results in significant
morbidity and mortality. The skeletal effects of glucocorticoids include both direct and …